AAH47085.1
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
16,250 Da
NCBI Official Full Name
Interleukin 33
NCBI Official Synonym Full Names
interleukin 33
NCBI Official Synonym Symbols
DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26 [Similar Products]
NCBI Protein Information
interleukin-33
UniProt Protein Name
Interleukin-33
UniProt Synonym Protein Names
Interleukin-1 family member 11; IL-1F11
UniProt Synonym Gene Names
NCBI Summary for IL33
The protein encoded by this gene is a cytokine that binds to the IL1RL1/ST2 receptor. The encoded protein is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
UniProt Comments for IL33
Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed:16286016). Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury (PubMed:17853410, PubMed:18836528).
Research Articles on IL33
Precautions
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Disclaimer
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Products associated withIL33 antibody pair kit
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Diseases associated with IL33 antibody pair kit
Organs/Tissues associated with IL33 antibody pair kit
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