AAB59436.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,791 Da
NCBI Official Full Name
interleukin 8 receptor alpha
NCBI Official Synonym Full Names
C-X-C motif chemokine receptor 1
NCBI Official Synonym Symbols
C-C; CD128; CD181; CKR-1; IL8R1; IL8RA; CMKAR1; IL8RBA; CDw128a; C-C-CKR-1 [Similar Products]
NCBI Protein Information
C-X-C chemokine receptor type 1
UniProt Protein Name
C-X-C chemokine receptor type 1
UniProt Synonym Protein Names
CDw128a; High affinity interleukin-8 receptor A; IL-8R A; IL-8 receptor type 1; CD_antigen: CD181
UniProt Synonym Gene Names
NCBI Summary for IL8Ra
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008]
UniProt Comments for IL8Ra
Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.
Research Articles on IL8Ra
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Disclaimer
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Pathways associated with IL8Ra elisa kit
Diseases associated with IL8Ra elisa kit
Organs/Tissues associated with IL8Ra elisa kit
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