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INHA cdna clone

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Catalog # MBS1276355
Unit / Price
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
INHA cdna clone
Product Name

INHA, cDNA Clone

Popular Item
Full Product Name

INHA cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggtgctgc acctactgct cttcttgctg ctgaccccac agggtgggca cagctgccag gggctggagc tggcccggga acttgttctg gccaaggtga gggccctgtt cttggatgcc ttggggcccc ccgcggtgac cagggaaggt ggggaccctg gagtcaggcg gctgccccga agacatgccc tggggggctt cacacacagg ggctctgagc ccgaggaaga ggaggatgtc tcccaagcca tccttttccc agccacagat gccagctgtg aggacaagtc agctgccaga gggctggccc aggaggctga ggagggcctc ttcagataca tgttccggcc atcccagcat acacgcagcc gccaggtgac ttcagcccag ctgtggttcc acaccgggct ggacaggcag ggcacagcag cctccaatag ctctgagccc ctgctaggcc tgctggcact gtcaccggga ggacccgtgg ctgtgcccat gtctttgggc catgctcccc ctcactgggc cgtgctgcac ctggccacct ctgctctctc tctgctgacc caccccgtcc tggtgctgct gctgcgctgt cccctctgta cctgctcagc ccggcctgag gccacgccct tcctggtggc ccacactcgg accagaccac ccagtggagg ggagagagcc cgacgctcaa ctcccctgat gtcctggcct tggtctccct ctgctctgcg cctgctgcag aggcctccgg aggaaccggc tgcccatgcc aactgccaca gagtagcact gaacatctcc ttccaggagc tgggctggga acggtggatc gtgtaccctc ccagtttcat cttccactac tgtcatggtg gttgtgggct gcacatccca ccaaacctgt cccttccagt ccctggggct ccccctaccc cagcccagcc ctactccttg ctgccagggg cccagccctg ctgtgctgct ctcccaggga ccatgaggcc cctacatgtc cgcaccacct cggatggagg ttactctttc aagtatgaga cagtgcccaa ccttctcacg cagcactgtg cttgtatcta a
OMIM
147380
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of INHA cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for INHA. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,670 Da
NCBI Official Full Name
Homo sapiens inhibin, alpha, mRNA
NCBI Official Synonym Full Names
inhibin alpha subunit
NCBI Official Symbol
NCBI Protein Information
inhibin alpha chain
UniProt Protein Name
Inhibin alpha chain
Protein Family
UniProt Gene Name
UniProt Entry Name
INHA_HUMAN
NCBI Summary for INHA
This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate multiple peptide products, including the alpha subunit of the inhibin A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion. Mutations in this gene may be associated with male infertility and premature ovarian failure in female human patients. [provided by RefSeq, Aug 2016]
UniProt Comments for INHA
INHA: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. Belongs to the TGF-beta family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: extracellular region

Molecular Function: cytokine activity; growth factor activity; hormone activity; protein binding; receptor binding; transforming growth factor beta receptor binding

Biological Process: cell cycle arrest; cell development; cell differentiation; cell surface receptor linked signal transduction; cell-cell signaling; hemoglobin biosynthetic process; negative regulation of B cell differentiation; negative regulation of cell cycle; negative regulation of interferon-gamma biosynthetic process; negative regulation of macrophage differentiation; negative regulation of phosphorylation; positive regulation of follicle-stimulating hormone secretion; regulation of apoptosis; regulation of cell cycle; regulation of cell proliferation; regulation of MAPKKK cascade; response to external stimulus; signal transduction; skeletal development
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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