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IPO11 elisa kit :: Human importin 11 ELISA Kit

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Catalog # MBS9317998
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  48-Strip-Wells  /  $470 +1 FREE 8GB USB
  96-Strip-Wells  /  $680 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
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IPO11 elisa kit
Product Name

importin 11 (IPO11), ELISA Kit

Full Product Name

Human Importin-11, IPO11 ELISA Kit

Product Synonym Names
Human Importin-11 (IPO11) ELISA kit; RanBP11; Ran binding protein 11; importin 11
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
610889
3D Structure
ModBase 3D Structure for Q9UI26
Species Reactivity
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of IPO11 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for IPO11purchase
MBS9317998 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the importin 11 (IPO11) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IPO11. The ELISA analytical biochemical technique of the MBS9317998 kit is based on IPO11 antibody-IPO11 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IPO11 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IPO11. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for IPO11. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
112,535 Da
NCBI Official Full Name
importin-11 isoform 1
NCBI Official Synonym Full Names
importin 11
NCBI Official Symbol
IPO11  [Similar Products]
NCBI Official Synonym Symbols
RanBP11
  [Similar Products]
NCBI Protein Information
importin-11; imp11; Ran binding protein 11; ran-binding protein 11
UniProt Protein Name
Importin-11
UniProt Synonym Protein Names
Ran-binding protein 11; RanBP11
Protein Family
UniProt Gene Name
IPO11  [Similar Products]
UniProt Synonym Gene Names
RANBP11; Imp11; RanBP11  [Similar Products]
UniProt Entry Name
IPO11_HUMAN
NCBI Summary for IPO11
Importins, including IPO11, are a members of the karyopherin/importin-beta family of transport receptors (see KPNB1; 602738) that mediate nucleocytoplasmic transport of protein and RNA cargoes (Plafker and Macara, 2000 [PubMed 11032817]).[supplied by OMIM, Sep 2008]
UniProt Comments for IPO11
IPO11: Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates the nuclear import of UBE2E3, and of RPL12. Belongs to the importin beta family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear import; Karyopherin

Chromosomal Location of Human Ortholog: 5q12.1

Cellular Component: cytoplasm; nucleus

Molecular Function: Ran GTPase binding; protein transporter activity

Biological Process: ribosomal protein import into nucleus
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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