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IRF5 cdna clone

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Catalog # MBS1267722
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
IRF5 cdna clone
Product Name

IRF5, cDNA Clone

Popular Item
Full Product Name

IRF5 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgaaccagt ccatcccagt ggctcccacc ccaccccgcc gcgtgcggct gaagccctgg ctggtggccc aggtgaacag ctgccagtac ccagggcttc aatgggtcaa cggggaaaag aaattattct gcatcccctg gaggcatgcc acaaggcatg gtcccagcca ggacggagat aacaccatct tcaaggcctg ggccaaggag acagggaaat acaccgaagg cgtggatgaa gccgatccgg ccaagtggaa ggccaacctg cgctgtgccc ttaacaagag ccgggacttc cgcctcatct acgacgggcc ccgggacatg ccacctcagc cctacaagat ctacgaggtc tgctccaatg gccctgctcc cacagactcc cagccccctg aggattactc ttttggtgca ggagaggagg aggaagaaga ggaagagctg cagaggatgt tgccaagcct gagcctcaca gaggatgtca agtggccgcc cactctgcag ccgcccactc tgcggccgcc tactctgcag ccgcccactc tgcagccgcc cgtggtgctg ggtccccctg ctccagaccc cagccccctg gctcctcccc ctggcaaccc tgctggcttc agggagcttc tctctgaggt cctggagcct gggcccctgc ctgccagcct gccccctgca ggcgaacagc tcctgccaga cctgctgatc agcccccaca tgctgcctct gaccgacctg gagatcaagt ttcagtaccg ggggcggcca ccccgggccc tcaccatcag caacccccat ggctgccggc tcttctacag ccagctggag gccacccagg agcaggtgga actcttcggc cccataagcc tggagcaagt gcgcttcccc agccctgagg acatccccag tgacaagcag cgcttctaca cgaaccagct gctggatgtc ctggaccgcg ggctcatcct ccagctacag ggccaggacc tttatgccat ccgcctgtgt cagtgcaagg tgttctggag cgggccttgt gcctcagccc atgactcatg ccccaacccc atccagcggg aggtcaagac caagcttttc agcctggagc attttctcaa tgagctcatc ctgttccaaa agggccagac caacacccca ccacccttcg agatcttctt ctgctttggg gaagaatggc ctgaccgcaa accccgagag aagaagctca ttactgtaca ggtggtgcct gtagcagctc gactgctgct ggagatgttc tcaggggagc tatcttggtc agctgatagt atccggctac agatctcaaa cccagacctc aaagaccgca tggtggagca attcaaggag ctccatcaca tctggcagtc ccagcagcgg ttgcagcctg tggcccaggc ccctcctgga gcaggccttg gtgttggcca ggggccctgg cctatgcacc cagctggcat gcaataa
OMIM
180300
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of IRF5 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for IRF5. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
17,020 Da
NCBI Official Full Name
Homo sapiens interferon regulatory factor 5, mRNA
NCBI Official Synonym Full Names
interferon regulatory factor 5
NCBI Official Symbol
NCBI Official Synonym Symbols
SLEB10
  [Similar Products]
NCBI Protein Information
interferon regulatory factor 5
UniProt Protein Name
Interferon regulatory factor 5
UniProt Gene Name
UniProt Synonym Gene Names
IRF-5  [Similar Products]
UniProt Entry Name
IRF5_HUMAN
NCBI Summary for IRF5
This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq, Mar 2010]
UniProt Comments for IRF5
IRF5: Transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Activated by TLR7 or TLR8 signaling. Homodimer, when phosphorylated. Belongs to the IRF family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 7q32

Cellular Component: cytoplasm; cytosol; nucleus

Molecular Function: protein binding

Biological Process: positive regulation of apoptosis; positive regulation of interferon-alpha production; positive regulation of interferon-beta production; positive regulation of interleukin-12 production; positive regulation of transcription from RNA polymerase II promoter; response to muramyl dipeptide; response to peptidoglycan

Disease: Inflammatory Bowel Disease 14; Systemic Lupus Erythematosus, Susceptibility To, 10
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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