NP_001240751.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
52,693 Da
NCBI Official Full Name
iroquois-class homeodomain protein IRX-3 isoform 1
NCBI Official Synonym Full Names
Iroquois related homeobox 3
NCBI Official Synonym Symbols
NCBI Protein Information
iroquois-class homeodomain protein IRX-3; homeodomain protein IRXB1; iroquois homeobox protein 3
UniProt Protein Name
Iroquois-class homeodomain protein IRX-3
UniProt Synonym Protein Names
Homeodomain protein IRXB1; Iroquois homeobox protein 3
UniProt Synonym Gene Names
UniProt Entry Name
IRX3_MOUSE
UniProt Comments for IRX3
IRX3: Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells. Belongs to the TALE/IRO homeobox family.
Protein type: DNA-binding
Cellular Component: axon; cytoplasm; nucleus
Molecular Function: DNA binding; sequence-specific DNA binding
Biological Process: negative regulation of neuron differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; multicellular organismal development; mesoderm development; positive regulation of neuron differentiation; kidney development
Research Articles on IRX3
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with IRX3 elisa kit
Organs/Tissues associated with IRX3 elisa kit
|