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ITLN1 recombinant protein :: Omentin Recombinant Protein

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Catalog # MBS142178
Unit / Price
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  0.002 mg  /  $140 +1 FREE 8GB USB
  0.01 mg  /  $205 +1 FREE 8GB USB
  1 mg  /  $5,025 +6 FREE 8GB USB
ITLN1 recombinant protein
Product Name

Omentin (ITLN1), Recombinant Protein

Popular Item
Full Product Name

Recombinant Human Omentin

Product Synonym Names
Omentin Human; Omentin Human Recombinant; Intelectin-1; HL1; LFR; HL-1; INTL; ITLN; hIntL; Omentin
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MNQLSFLLFL IATTRGWSTD EANTYFKEWT CSSSPSLPRS CKEIKDECPS AFDGLYFLRT ENGVIYQTFC DMTSGGGGWT LVASVHENDM RGKCTVGDRW SSQQGSKADY PEGDGNWANY NTFGSAEAAT SDDYKNPGYY DIQAKDLGIW HVPNKSPMQH WRNSSLLRYR TDTGFLQTLG HNLFGIYQKY PVKYGEGKCW TDNGPVIPVV YDFGDAQKTA SYYSPYGQRE FNNERAANAL CAGMRVTGCN TEHHCIGGGG YFPEASPQQC GDFSGFDWSG YGTHVGYSSS REITEAAVLL FYR
OMIM
609873
3D Structure
ModBase 3D Structure for Q8WWA0
Host
E Coli
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Form/Format
Each mg of lyophilized powder contains 20mM NaP, pH-7.5 and 0.5% manntiol.
Sterile Filtered White lyophilized (freeze-dried) powder.
Solubility
It is recommended to reconstitute the lyophilized Omentin in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Preparation and Storage
Lyophilized Intelectin although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Intelectin should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Other Notes
Small volumes of ITLN1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ITLN1 recombinant protein
Description: Omentin Human Recombinant is produced in E Coli by recombinant DNA technology is a single, polypeptide chain containing 313 amino acids and having a molecular mass of 35 kDa. Intelectin is purified by proprietary chromatographic techniques.

Introduction: Omentin is a recently recognized gene highly localized to the mental tissue (visceral adipose tissue). Omentin is present in the stromal vascular cells in the adipose tissue rather than in the adipocytes. Omentin is predominantly expressed in the visceral adipose tissue than the subcutaneous tissue, with the omentin mRNA being 150 times higher in the visceral adipose tissue. Omentin has also been detected in human blood using western blot analysis, and seems to increase insulin-stimulated glucose uptake in 3T3-L1 adipocytes in mice. Omentin seems to increase Akt phosphorylation irrespective of insulin presence. Its role in glucose metabolism and obesity remains to be described; an insulin-sensitizing action is possible.Differences in Omentin expression has been noted in adipose tissue from normals and patients with inflammatory bowel disease although its significance is unknown.
NCBI/Uniprot data below describe general gene information for ITLN1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
34,962 Da[Similar Products]
NCBI Official Full Name
intelectin-1
NCBI Official Synonym Full Names
intelectin 1 (galactofuranose binding)
NCBI Official Symbol
ITLN1  [Similar Products]
NCBI Official Synonym Symbols
HL1; LFR; HL-1; INTL; ITLN; hIntL; omentin
  [Similar Products]
NCBI Protein Information
intelectin-1; ITLN-1; endothelial lectin HL-1; galactofuranose-binding lectin; intestinal lactoferrin receptor
UniProt Protein Name
Intelectin-1
UniProt Synonym Protein Names
Endothelial lectin HL-1; Galactofuranose-binding lectin; Intestinal lactoferrin receptor; Omentin
Protein Family
UniProt Gene Name
ITLN1  [Similar Products]
UniProt Synonym Gene Names
INTL; ITLN; LFR; ITLN-1  [Similar Products]
UniProt Entry Name
ITLN1_HUMAN
UniProt Comments for ITLN1
ITLN1: Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: brush border membrane; receptor complex; lipid raft

Molecular Function: carbohydrate binding

Biological Process: positive regulation of glucose import; response to nematode; positive regulation of protein amino acid phosphorylation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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