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ITM2C elisa kit :: Sheep Integral membrane protein 2C (ITM2C) ELISA Kit

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Catalog # MBS7237613
Unit / Price
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  48-Strip-Wells  /  $440 +1 FREE 8GB USB
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ITM2C elisa kit
Product Name

Integral membrane protein 2C (ITM2C), ELISA Kit

Full Product Name

Sheep Integral membrane protein 2C (ITM2C) ELISA Kit

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
609554
Species Reactivity
Samples
Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
Preparation and Storage
Store all reagents at 2-8 degree C.
Sample Preparation
We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of ITM2C elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forITM2Cpurchase
MBS7237613 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Integral membrane protein 2C (ITM2C) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ITM2C. The ELISA analytical biochemical technique of the MBS7237613 kit is based on ITM2C antibody-ITM2C antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ITM2C antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ITM2C. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Product Categories/Family for ITM2C elisa kit
NCBI/Uniprot data below describe general gene information for ITM2C. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
25,921 Da
NCBI Official Full Name
Integral membrane protein 2C
NCBI Official Synonym Full Names
integral membrane protein 2C
NCBI Official Symbol
ITM2C  [Similar Products]
NCBI Official Synonym Symbols
E25; BRI3; E25C; ITM3; BRICD2C
  [Similar Products]
NCBI Protein Information
integral membrane protein 2C; cerebral protein 14; transmembrane protein BRI3; integral membrane protein 3; BRICHOS domain containing 2C
UniProt Protein Name
Integral membrane protein 2C
UniProt Synonym Protein Names
Cerebral protein 14; Transmembrane protein BRI3Cleaved into the following chain:CT-BRI3
Protein Family
UniProt Gene Name
ITM2C  [Similar Products]
UniProt Synonym Gene Names
BRI3; hucep-14; NPD018; PSEC0047  [Similar Products]
UniProt Entry Name
ITM2C_HUMAN
UniProt Comments for ITM2C
ITM2C: Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C- terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation. Belongs to the ITM2 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q37

Cellular Component: Golgi apparatus; lysosomal membrane; perinuclear region of cytoplasm; lysosome; plasma membrane; integral to membrane

Molecular Function: protein binding; beta-amyloid binding; ATP binding

Biological Process: neuron differentiation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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