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KAL1 blocking peptide

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Catalog # MBS9224077
Unit / Price
  0.1 mg  /  $155 +1 FREE 8GB USB
KAL1 blocking peptide
Product Name

KAL1, Blocking Peptide

Full Product Name

KAL1 Antibody (N-term) Blocking Peptide

Product Synonym Names
Anosmin-1; Adhesion molecule-like X-linked; Kallmann syndrome protein; KAL1; ADMLX; KAL; KALIG1
Product Synonym Gene Name
ADMLX; KAL; KALIG1[Similar Products]
Antibody/Peptide Pairs
KAL1 peptide (MBS9224077) is used for blocking the activity of KAL1 antibody (MBS9212093)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
300836
3D Structure
ModBase 3D Structure for P23352
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Cell membrane; Peripheral membrane protein. Secreted. Note: Proteolytic cleavage may release it from the cell surface into the extracellular space
Tissue Location
Expressed in the cerebellum (at protein level).
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of KAL1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
KAL1 blocking peptide
Has a dual branch-promoting and guidance activity, which may play an important role in the patterning of mitral and tufted cell collaterals to the olfactory cortex (By similarity). Chemoattractant for fetal olfactory epithelial cells.
NCBI/Uniprot data below describe general gene information for KAL1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
76,112 Da
NCBI Official Full Name
Anosmin-1
NCBI Official Synonym Full Names
anosmin 1
NCBI Official Symbol
ANOS1  [Similar Products]
NCBI Official Synonym Symbols
HH1; HHA; KAL; KMS; KAL1; ADMLX; WFDC19; KALIG-1
  [Similar Products]
NCBI Protein Information
anosmin-1
UniProt Protein Name
Anosmin-1
UniProt Synonym Protein Names
Adhesion molecule-like X-linked; Kallmann syndrome protein
UniProt Gene Name
ANOS1  [Similar Products]
UniProt Entry Name
KALM_HUMAN
NCBI Summary for KAL1
Mutations in this gene cause the X-linked Kallmann syndrome. The encoded protein is similar in sequence to proteins known to function in neural cell adhesion and axonal migration. In addition, this cell surface protein is N-glycosylated and may have anti-protease activity. [provided by RefSeq, Jul 2008]
UniProt Comments for KAL1
KAL1: Has a dual branch-promoting and guidance activity, which may play an important role in the patterning of mitral and tufted cell collaterals to the olfactory cortex. Chemoattractant for fetal olfactory epithelial cells. Defects in KAL1 are the cause of Kallmann syndrome type 1 (KAL1); also known as hypogonadotropic hypogonadism and anosmia. Anosmia or hyposmia is related to the absence or hypoplasia of the olfactory bulbs and tracts. Hypogonadism is due to deficiency in gonadotropin-releasing hormone and probably results from a failure of embryonic migration of gonadotropin- releasing hormone-synthesizing neurons. In some patients other developmental anomalies can be present, which include renal agenesis, cleft lip and/or palate, selective tooth agenesis, and bimanual synkinesis. In some cases anosmia may be absent or inconspicuous.

Protein type: Motility/polarity/chemotaxis; Extracellular matrix

Chromosomal Location of Human Ortholog: Xp22.32

Cellular Component: extracellular region; extracellular space; proteinaceous extracellular matrix

Molecular Function: extracellular matrix structural constituent; protein binding

Biological Process: axon guidance; cell motility; chemotaxis; fibroblast growth factor receptor signaling pathway

Disease: Hypogonadotropic Hypogonadism 1 With Or Without Anosmia
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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