NP_037480.1
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NCBI GenBank Nucleotide #
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UniProt Related Accession #
Molecular Weight
47,846 Da
NCBI Official Full Name
ATP-sensitive inward rectifier potassium channel 14
NCBI Official Synonym Full Names
potassium inwardly-rectifying channel, subfamily J, member 14
NCBI Official Synonym Symbols
NCBI Protein Information
ATP-sensitive inward rectifier potassium channel 14; IRK-4; inward rectifier K(+) channel Kir2.4; inwardly rectifying potassium channel KIR2.4; potassium channel, inwardly rectifying subfamily J member 14
UniProt Protein Name
ATP-sensitive inward rectifier potassium channel 14
UniProt Synonym Protein Names
Inward rectifier K(+) channel Kir2.4; IRK-4; Potassium channel, inwardly rectifying subfamily J member 14
UniProt Synonym Gene Names
UniProt Entry Name
KCJ14_HUMAN
NCBI Summary for KCNJ14
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel, and probably has a role in controlling the excitability of motor neurons. [provided by RefSeq, Feb 2013]
UniProt Comments for KCNJ14
KCNJ14: Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ14 gives rise to low-conductance channels with a low affinity to the channel blockers Barium and Cesium. Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ14 subfamily.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 19q13
Cellular Component: voltage-gated potassium channel complex; cell soma; dendrite; plasma membrane
Molecular Function: inward rectifier potassium channel activity
Biological Process: synaptic transmission; potassium ion import
Research Articles on KCNJ14
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Products associated with KCNJ14 elisa kit
Pathways associated with KCNJ14 elisa kit
Diseases associated with KCNJ14 elisa kit
Organs/Tissues associated with KCNJ14 elisa kit
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