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KCNN2 elisa kit :: Human Potassium Intermediate Small Conductance Calcium Activated Channel Subfamily N, Member 2 ELISA Kit

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Catalog # MBS070265
Unit / Price
  48-Strip-Wells  /  $470 +1 FREE 8GB USB
  96-Strip-Wells  /  $680 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
KCNN2 elisa kit
Product Name

Potassium Intermediate Small Conductance Calcium Activated Channel Subfamily N, Member 2 (KCNN2), ELISA Kit

Full Product Name

Human Potassium Intermediate Small Conductance Calcium Activated Channel Subfamily N, Member 2 ELISA Kit

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
605879
3D Structure
ModBase 3D Structure for Q9H2S1
Species Reactivity
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of KCNN2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forKCNN2purchase
MBS070265 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Potassium Intermediate Small Conductance Calcium Activated Channel Subfamily N, Member 2 (KCNN2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing KCNN2. The ELISA analytical biochemical technique of the MBS070265 kit is based on KCNN2 antibody-KCNN2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect KCNN2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, KCNN2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for KCNN2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
63,760 Da
NCBI Official Full Name
small conductance calcium-activated potassium channel protein 2 isoform X1
NCBI Official Synonym Full Names
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
NCBI Official Symbol
KCNN2  [Similar Products]
NCBI Official Synonym Symbols
SK2; hSK2; SKCA2; KCa2.2; SKCa 2
  [Similar Products]
NCBI Protein Information
small conductance calcium-activated potassium channel protein 2; apamin-sensitive small-conductance Ca2+-activated potassium channel
UniProt Protein Name
Small conductance calcium-activated potassium channel protein 2
UniProt Synonym Protein Names
KCa2.2
UniProt Gene Name
KCNN2  [Similar Products]
UniProt Synonym Gene Names
SK2; SKCa 2; SKCa2  [Similar Products]
UniProt Entry Name
KCNN2_HUMAN
NCBI Summary for KCNN2
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
UniProt Comments for KCNN2
KCNN2: Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin. Belongs to the potassium channel KCNN family. KCa2.2/KCNN2 subfamily.

Protein type: Channel, potassium; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 5q22.3

Cellular Component: smooth endoplasmic reticulum; cell soma; T-tubule; dendritic spine; plasma membrane; integral to membrane; Z disc

Molecular Function: calmodulin binding; calcium-activated potassium channel activity; protein homodimerization activity; alpha-actinin binding; small conductance calcium-activated potassium channel activity

Biological Process: synaptic transmission; potassium ion transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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