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KCNN3 elisa kit :: Human potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 ELISA Kit

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Catalog # MBS9316308
Unit / Price
  48-Strip-Wells  /  $470 +1 FREE 8GB USB
  96-Strip-Wells  /  $680 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
KCNN3 elisa kit
Product Name

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 (KCNN3), ELISA Kit

Full Product Name

Human Small conductance calcium-activated potassium channel protein 3, KCNN3 ELISA Kit

Product Synonym Names
Human Small conductance calcium-activated potassium channel protein 3 (KCNN3) ELISA kit; KCa2.3; SK3; SKCA3; hSK3; small conductance calcium-activated potassium channel protein 3; potassium intermediate/small conductance calcium-activated channel; subfamily N; member 3
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
602983
3D Structure
ModBase 3D Structure for Q9UGI6
Species Reactivity
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of KCNN3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forKCNN3purchase
MBS9316308 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 (KCNN3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing KCNN3. The ELISA analytical biochemical technique of the MBS9316308 kit is based on KCNN3 antibody-KCNN3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect KCNN3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, KCNN3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for KCNN3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
82,026 Da
NCBI Official Full Name
small conductance calcium-activated potassium channel protein 3 isoform c
NCBI Official Synonym Full Names
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
NCBI Official Symbol
KCNN3  [Similar Products]
NCBI Official Synonym Symbols
SK3; hSK3; SKCA3; KCa2.3
  [Similar Products]
NCBI Protein Information
small conductance calcium-activated potassium channel protein 3; SKCa 3
UniProt Protein Name
Small conductance calcium-activated potassium channel protein 3
UniProt Synonym Protein Names
KCa2.3
UniProt Gene Name
KCNN3  [Similar Products]
UniProt Synonym Gene Names
K3; SK3; SKCa 3; SKCa3  [Similar Products]
UniProt Entry Name
KCNN3_HUMAN
NCBI Summary for KCNN3
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel, which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
UniProt Comments for KCNN3
KCNN3: Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin. Belongs to the potassium channel KCNN family. KCa2.3/KCNN3 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: cell soma; integral to membrane; plasma membrane

Molecular Function: calmodulin binding; small conductance calcium-activated potassium channel activity

Biological Process: synaptic transmission
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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