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KCNQ1 elisa kit :: Human voltage-gated potassium channel antibody (VGKC-ab) ELISA Kit

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Catalog # MBS702366
Unit / Price
  24-Strip-Wells (LIMIT 1)  /  $240 +1 FREE 8GB USB
  48-Strip-Wells  /  $590 +1 FREE 8GB USB
  96-Strip-Wells  /  $855 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $3,110 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $5,890 +7 FREE 8GB USB
Typical Testing Data/Standard Curve (for reference only)
Product Name

voltage-gated potassium channel antibody (VGKC-ab) (KCNQ1), ELISA Kit

Also Known As

Human voltage-gated potassium channel antibody, VGKC-ab ELISA Kit

Product Synonym Names
Human voltage-gated potassium channel antibody (VGKC-ab) ELISA Kit; voltage-gated potassium channel antibody (VGKC-ab)
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
MBS702366 Testing Data
Sequence Length
581
OMIM
609621
3D Structure
ModBase 3D Structure for P51787
Species Reactivity
Samples
Serum
Detection Wavelength
450 nm
Sample Volume
50-100ul
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of KCNQ1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forKCNQ1purchase
MBS702366 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the voltage-gated potassium channel antibody (VGKC-ab) (KCNQ1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing KCNQ1. The ELISA analytical biochemical technique of the MBS702366 kit is based on KCNQ1 antibody-KCNQ1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect KCNQ1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, KCNQ1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Related Product Information for
KCNQ1 elisa kit
Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with specificity antigen . Samples are then added to the appropriate microtiter plate wells and incubated. Then add Horseradish Peroxidase (HRP)-conjugated -anti-human immunoglobin to each well and incubate. Finally, substrate solutions are added to each well. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. Calculate the valence of human anti-VGKC antibody in the samples.

Typical Testing Data/Standard Curve (for reference only) of KCNQ1 elisa kit
KCNQ1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
Sample Manual Insert of MBS702366. Click to request current manual
NCBI/Uniprot data below describe general gene information for KCNQ1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
61,474 Da[Similar Products]
NCBI Official Full Name
voltage gated potassium channel
NCBI Official Synonym Full Names
potassium voltage-gated channel, KQT-like subfamily, member 1
NCBI Official Symbol
KCNQ1  [Similar Products]
NCBI Official Synonym Symbols
LQT; RWS; WRS; LQT1; SQT2; ATFB1; ATFB3; JLNS1; KCNA8; KCNA9; Kv1.9; Kv7.1; KVLQT1
  [Similar Products]
NCBI Protein Information
potassium voltage-gated channel subfamily KQT member 1; slow delayed rectifier channel subunit; voltage-gated potassium channel subunit Kv7.1; kidney and cardiac voltage dependend K+ channel; IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1
UniProt Protein Name
Potassium voltage-gated channel subfamily KQT member 1
UniProt Synonym Protein Names
IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1; KQT-like 1; Voltage-gated potassium channel subunit Kv7.1
UniProt Gene Name
KCNQ1  [Similar Products]
UniProt Synonym Gene Names
KCNA8; KCNA9; KVLQT1  [Similar Products]
UniProt Entry Name
KCNQ1_HUMAN
NCBI Summary for KCNQ1
This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
UniProt Comments for KCNQ1
Function: Probably important in cardiac repolarization. Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current. Elicits a rapidly activating, potassium-selective outward current. Muscarinic agonist oxotremorine-M strongly suppresses KCNQ1/KCNE1 current in CHO cells in which cloned KCNQ1/KCNE1 channels were coexpressed with M1 muscarinic receptors. May associate also with KCNE3 (MiRP2) to form the potassium channel that is important for cyclic AMP-stimulated intestinal secretion of chloride ions, which is reduced in cystic fibrosis and pathologically stimulated in cholera and other forms of secretory diarrhea.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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