BC015947
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
56,001 Da
NCBI Official Full Name
Homo sapiens potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3, mRNA
NCBI Official Synonym Full Names
potassium voltage-gated channel modifier subfamily S member 3
NCBI Official Synonym Symbols
NCBI Protein Information
potassium voltage-gated channel subfamily S member 3
UniProt Protein Name
Potassium voltage-gated channel subfamily S member 3
UniProt Synonym Protein Names
Delayed-rectifier K(+) channel alpha subunit 3; Voltage-gated potassium channel subunit Kv9.3
UniProt Entry Name
KCNS3_HUMAN
NCBI Summary for KCNS3
Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2013]
UniProt Comments for KCNS3
Kv9.3: Potassium channel subunit. Modulates channel activity and reduces the ion flow. Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.3/KCNS3 sub-subfamily.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 2p24
Cellular Component: cytoplasm; Golgi apparatus; integral to membrane; plasma membrane
Molecular Function: delayed rectifier potassium channel activity; potassium channel regulator activity
Biological Process: potassium ion transport; regulation of insulin secretion
Research Articles on KCNS3
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Pathways associated with KCNS3 cdna clone
Diseases associated with KCNS3 cdna clone
Organs/Tissues associated with KCNS3 cdna clone
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