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KHK recombinant protein :: Ketohexokinase Recombinant Protein

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Catalog # MBS203439
Unit / Price
  0.1 mg  /  $285 +1 FREE 8GB USB
  0.5 mg  /  $640 +1 FREE 8GB USB
SDS-Page
Product Name

Ketohexokinase (KHK), Recombinant Protein

Also Known As

Ketohexokinase, 1-298aa, Human, E Coli

Product Synonym Names
KHK; Hepatic fructokinase; EC 2.7.1.3; Hepatic fructokinase; ketohexokinase; Ketohexokinase isoform a
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
298
Sequence
MEEKQILCVG LVVLDVISLV DKYPKEDSEI RCLSQRWQRG GNASNSCTIL SLLGAPCAFM GSMAPGHVAD FVLDDLRRYS VDLRYTVFQT TGSVPIATVI INEASGSRTI LYYDRSLPDV SATDFEKVDL TQFKWIHIEG RNASEQVKML QRIDAHNTRQ PPEQKIRVSV EVEKPREELF QLFGYGDVVF VSKDVAKHLG FQSAEEALRG LYGRVRKGAV LVCAWAEEGA DALGPDGKLL HSDAFPPPRV VDTLGAGDTF NASVIFSLSQ GRSVQEALRF GCQVAGKKCG LQGFDGIV
OMIM
X78678 mRNA
Host
E Coli
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid. In phosphate-buffered saline (pH 7.4) containing 10% glycerol
Concentration
1 mg/ml (determined by Bradford assay) (lot specific)
Antigen Species
Human
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Other Notes
Small volumes of KHK recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
KHK recombinant protein
Ketohexokinase is an enzyme that catalyzes the phosphorylation of fructose to produce fructose-1-phosphate, leading to consumption of ATP, formation of AMP. This protein initiates first step in the metabolism of dietary fructose and is an important regulator of hepatic glucose metabolism. It is highly found in liver, renal cortex, and small intestine. Its deficiency causes the benign hereditary metabolic disorder essential fructosuria, leading to fructose being excreted in the urine. Recombinant human Ketohexokinase was expressed in E Coli and purified by using conventional chromatography.
Product Categories/Family for KHK recombinant protein
Applications Tested/Suitable for KHK recombinant protein
SDS-PAGE

NCBI/Uniprot data below describe general gene information for KHK. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
32.7 kDa (298aa), confirmed by MALDI-TOF. [Similar Products]
NCBI Official Full Name
Ketohexokinase (fructokinase)
NCBI Official Synonym Full Names
ketohexokinase
NCBI Official Symbol
NCBI Protein Information
ketohexokinase
UniProt Protein Name
Ketohexokinase
UniProt Synonym Protein Names
Hepatic fructokinase
Protein Family
UniProt Gene Name
NCBI Summary for KHK
This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
UniProt Comments for KHK
Catalyzes the phosphorylation of the ketose sugar fructose to fructose-1-phosphate.
Product References and Citations for KHK recombinant protein
Bonthron DT., et al. (2009) J Histochem Cytochem. 57 (8):763-74.; Schermerhorn T., et al. (2009) Res Vet Sci. 87 (1):115-7. ;

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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