NP_859043.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
14,188 Da
NCBI Official Full Name
metastasis-suppressor KiSS-1
NCBI Official Synonym Full Names
KiSS-1 metastasis-suppressor
NCBI Official Synonym Symbols
NCBI Protein Information
metastasis-suppressor KiSS-1; metastin; kisspeptin-1; MLL septin-like fusion; Kiss1 variant E1a-E2b-E3; Kiss1 variant E1b-E2a-E3; Kiss1 variant E1b-E2b-E3
UniProt Protein Name
Metastasis-suppressor KiSS-1
UniProt Synonym Protein Names
Kisspeptin-1Cleaved into the following 2 chains:Metastin; Kisspeptin-10Alternative name(s):Metastin45-54
UniProt Entry Name
KISS1_RAT
NCBI Summary for KISS1
ligand for the G-protein-coupled receptor GPR54; may be involved in autonomic and sensory neural signaling [RGD, Feb 2006]
UniProt Comments for KISS1
Function: Metastasis suppressor protein. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. Intracerebroventricular administration induces an increase in serum LH and FSH levels in prepubertal male and female as well as in adult animals.3 PublicationsManual assertion based on experiment in:Ref.2
Research Articles on KISS1
Precautions
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Disclaimer
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Products associated with KISS1 elisa kit
Pathways associated with KISS1 elisa kit
Diseases associated with KISS1 elisa kit
Disease Name |
Pubmed Publications |
Male Urogenital Diseases Antibodies |
>50 publications with KISS1 and Male Urogenital Diseases |
Genital Diseases, Female Antibodies |
>46 publications with KISS1 and Genital Diseases, Female |
Puberty, Precocious Antibodies |
>44 publications with KISS1 and Puberty, Precocious |
Infertility, Female Antibodies |
>40 publications with KISS1 and Infertility, Female |
Breast Neoplasms Antibodies |
>38 publications with KISS1 and Breast Neoplasms |
Pregnancy Complications Antibodies |
>31 publications with KISS1 and Pregnancy Complications |
Puberty, Delayed Antibodies |
>31 publications with KISS1 and Puberty, Delayed |
Adenocarcinoma Antibodies |
>27 publications with KISS1 and Adenocarcinoma |
Infertility, Male Antibodies |
>26 publications with KISS1 and Infertility, Male |
Ovarian Diseases Antibodies |
>21 publications with KISS1 and Ovarian Diseases |
Organs/Tissues associated with KISS1 elisa kit
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