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Klk14 recombinant protein :: Kallikrein-14 (Klk14) Recombinant Protein

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Catalog # MBS7092480
Unit / Price
  0.05 mg (E-Coli)  /  $625 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $845 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $930 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,305 +1 FREE 8GB USB
SDS-Page
Product Name

Kallikrein-14 (Klk14), Recombinant Protein

Popular Item
Also Known As

Recombinant Mouse Kallikrein-14 (Klk14)

Product Synonym Names
Glandular kallikrein KLK14
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
24-250aa; Full Length of Mature Protein
Sequence Length
250
Sequence
IIGGYRCVRN SQPWQVALQA GPGHRFLCGG VLLSDQWVIT AAHCARPILH VALGKHNIRR WEATQQVVRV ARQVPHPQYQ PQAHDNDLML LKLQKKVRLG RAVKTISVAS SCASPGTPCR VSGWGTIASP IARYPTALQC VNVNIMSEQA CHRAYPGIIT SGMVCAGVPE GGKDSCQGDS GGPLVCGGQL QGLVSWGMER CAMPGYPGVY ANLCNYHSWI QRTMQSN
3D Structure
ModBase 3D Structure for Q8CGR5
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Mus musculus (Mouse)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of Klk14 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Klk14 recombinant protein
Serine-type endopeptidase with a dual trypsin-like and chymotrypsin-like substrate specificity. May activate/inactivate the proteinase-activated receptors F2R, F2RL1 and F2RL3 and other kallikreins including KLK1, KLK3, KLK5 and KLK11. May function in seminal clot liquefaction through direct cleavage of the semenogelin SEMG1 and SEMG2 and activation of KLK3. May function through desmoglein DSG1 cleavage in epidermal desquamation a process by which the most superficial corneocytes are shed from the skin surface. May be involved in several aspects of tumor progression including growth, invasion and angiogenesis
Product Categories/Family for Klk14 recombinant protein

Klk14 recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for Klk14. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
NCBI Official Full Name
kallikrein-14 preproprotein
NCBI Official Synonym Full Names
kallikrein related-peptidase 14
NCBI Official Symbol
Klk14  [Similar Products]
NCBI Official Synonym Symbols
NCBI Protein Information
kallikrein-14
UniProt Protein Name
Kallikrein-14
UniProt Synonym Protein Names
Glandular kallikrein KLK14; mGK14; Kallikrein related-peptidase 14
Protein Family
UniProt Gene Name
Klk14  [Similar Products]
UniProt Synonym Gene Names
Gk14; mGK14  [Similar Products]
NCBI Summary for Klk14
This gene encodes a member of the kallikrein subfamily of serine proteases that have diverse physiological functions such as regulation of blood pressure and desquamation. The encoded protein is a precursor that undergoes proteolytic cleavage of the activation peptide to generate the functional enzyme. The encoded enzyme was found to activate the complement pathway by cleavage of C3 to release C3a anaphylotoxin. This gene is one of the several glandular kallikrein genes located in a cluster on chromosome 7. [provided by RefSeq, Aug 2015]
UniProt Comments for Klk14
Serine-type endopeptidase with a dual trypsin-like and chymotrypsin-like substrate specificity. May activate/inactivate the proteinase-activated receptors F2R, F2RL1 and F2RL3 and other kallikreins including KLK1, KLK3, KLK5 and KLK11. May function in seminal clot liquefaction through direct cleavage of the semenogelin SEMG1 and SEMG2 and activation of KLK3. May function through desmoglein DSG1 cleavage in epidermal desquamation a process by which the most superficial corneocytes are shed from the skin surface. May be involved in several aspects of tumor progression including growth, invasion and angiogenesis ().
Product References and Citations for Klk14 recombinant protein
"Taxon-specific evolution of glandular kallikrein genes and identification of a progenitor of prostate-specific antigen." Olsson A.Y., Lilja H., Lundwall A. Genomics 84:147-156(2004)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with Klk14 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Mammary Gland Antibodies  >1 publications with Klk14 and Mammary Gland
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