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KLK6 elisa kit :: Mouse Kallikrein 6 ELISA Kit

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Catalog # MBS721782
Unit / Price
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  48-Strip-Wells  /  $440 +1 FREE 8GB USB
  96-Strip-Wells  /  $640 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
Typical Testing Data/Standard Curve (for reference only)
Product Name

Kallikrein 6 (KLK6), ELISA Kit

Popular Item
Full Product Name

Mouse Kallikrein 6 ELISA Kit

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
602652
Species Reactivity
Samples
Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
Assay Type
Competitive
Detection Range
1.0-25ng/mL
Sensitivity
0.1ng/mL
Preparation and Storage
Store all reagents at 2-8 degree C.
Sample Preparation
We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of KLK6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for KLK6purchase
MBS721782 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Kallikrein 6 (KLK6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing KLK6. The ELISA analytical biochemical technique of the MBS721782 kit is based on KLK6 antibody-KLK6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect KLK6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, KLK6. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Product Categories/Family for KLK6 elisa kit

Typical Testing Data/Standard Curve (for reference only) of KLK6 elisa kit
KLK6 elisa kit Typical Testing Data/Standard Curve (for reference only) image
Sample Manual Insert of MBS721782. Click to request current manual
NCBI/Uniprot data below describe general gene information for KLK6. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
4,333 Da
NCBI Official Full Name
kallikrein-6 isoform B
NCBI Official Synonym Full Names
kallikrein-related peptidase 6
NCBI Official Symbol
NCBI Official Synonym Symbols
hK6; Bssp; Klk7; SP59; PRSS9; PRSS18
  [Similar Products]
NCBI Protein Information
kallikrein-6; zyme; neurosin; protease M; serine protease 9; serine protease 18
UniProt Protein Name
Kallikrein-6
UniProt Synonym Protein Names
Neurosin; Protease M; SP59; Serine protease 18; Serine protease 9; Zyme
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
PRSS18; PRSS9  [Similar Products]
UniProt Entry Name
KLK6_HUMAN
NCBI Summary for KLK6
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for KLK6
KLK6: Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in regulation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, suggesting a role in invasion and metastasis. Belongs to the peptidase S1 family. Kallikrein subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Protease; Secreted, signal peptide; EC 3.4.21.-; Nucleolus

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: microtubule cytoskeleton; nucleoplasm; extracellular space; intercellular bridge; nuclear membrane; mitochondrion; endoplasmic reticulum; cytoplasm; extracellular region; nucleolus

Molecular Function: protein binding; serine-type endopeptidase activity

Biological Process: myelination; protein autoprocessing; collagen catabolic process; central nervous system development; amyloid precursor protein metabolic process; tissue regeneration; regulation of cell differentiation; positive regulation of G-protein coupled receptor protein signaling pathway; response to wounding; hormone metabolic process; protein processing; proteolysis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with KLK6 elisa kit
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