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Klk7 recombinant protein :: Glandular kallikrein-7 Recombinant Protein

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Catalog # MBS949033
Unit / Price
Scan QR to view Datasheet
  0.01 mg (E-Coli)  /  $200 +1 FREE 8GB USB
  0.05 mg (E-Coli)  /  $260 +1 FREE 8GB USB
  0.1 mg (E-Coli)  /  $430 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $685 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,125 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,725 +2 FREE 8GB USB
SDS-PAGE
Product Name

Glandular kallikrein-7 (Klk7), Recombinant Protein

Popular Item
Full Product Name

Recombinant Rat Glandular kallikrein-7, submandibular/renal

Product Synonym Names
Esterase B; Kallikrein-related protein K1; Proteinase ARSKG-7; Tissue kallikrein
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
25-261aa; Full Length
Sequence
VIGGYKCEKN SQPWQVALYS FTKYLCGGVL IDPSWVITAA HCSSNNYQVW LGRNNLLEDE PFAQHRLVSQ SFPHPDYKPF LMRNHTRKPG DDHSNDLMLL HLSQPADITD GVKVIDLPTE EPKVGSTCLA SGWGSTKPLI WEFPDDLQCV NIHLLSNEKC IKAYKEKVTD LMLCAGELEG GKDTCTGDSG GPLLCDGVLQ GITSWGSVPC AKTNMPAIYT KLIKFTSWIK EVMKENP
3D Structure
ModBase 3D Structure for P36373
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater than 90% as determined by SDS-PAGE. (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of Klk7 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Klk7 recombinant protein
Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Predominant kallikrein protein in the kidney.

Klk7 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for Klk7. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
Molecular Weight
30.38kD
NCBI Official Full Name
kallikrein 1
UniProt Protein Name
Glandular kallikrein-7, submandibular/renal
UniProt Synonym Protein Names
Esterase B; Kallikrein-related protein K1; Proteinase A; RSKG-7; Tissue kallikrein
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
Klk-7; rGK-7  [Similar Products]
UniProt Entry Name
KLK7_RAT
NCBI Summary for Klk7
serine protease; involved in processing of bioactive peptides [RGD, Feb 2006]
UniProt Comments for Klk7
KLK7: May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. SCCE cleaves insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines. Belongs to the peptidase S1 family. Kallikrein subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; EC 3.4.21.35; Secreted, signal peptide; Protease

Cellular Component: acrosome; apical part of cell; nucleus

Molecular Function: endopeptidase activity; serine-type endopeptidase activity

Biological Process: positive regulation of acute inflammatory response; positive regulation of apoptosis; positive regulation of cell proliferation; proteolysis; response to nutrient
Product References and Citations for Klk7 recombinant protein
Molecular cloning and characterization of two rat renal kallikrein genes.Chen Y.-P., Chao J., Chao L.Biochemistry 27:7189-7196(1988) Characterization of serine proteinases isolated from rat submaxillary gland with special reference to the degradation of rat kininogens by these enzymes.Kato H., Nakanishi E., Enjyoji K., Hayashi I., Oh-Ishi S., Iwanaga S.J. Biochem. 102:1389-1404(1987) Substrate specificity of two kallikrein family gene products isolated from the rat submaxillary gland.Elmoujahed A., Gutman N., Brillard M., Gauthier F.FEBS Lett. 265:137-140(1990) The expression of two kallikrein gene family members in the rat kidney.Brady J.M., MacDonald R.J.Arch. Biochem. Biophys. 278:342-349(1990)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withKlk7 recombinant protein
 Reference Product  PubMed Publications
 Set recombinant protein  >4 publications with Klk7 and Set
Organs/Tissues associated with Klk7 recombinant protein
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