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Kng1 recombinant protein :: Kininogen-1 (Kng1) Recombinant Protein

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Catalog # MBS959356
Unit / Price
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  0.01 mg (Yeast)  /  $200 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $260 +1 FREE 8GB USB
  0.1 mg (Yeast)  /  $430 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $680 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,120 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,730 +2 FREE 8GB USB
SDS-Page
Product Name

Kininogen-1 (Kng1), Recombinant Protein

Popular Item
Full Product Name

Recombinant Rat Kininogen-1 (Kng1), partial

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
390-639aa, Full Length of Mature Protein
Sequence
APRVKKPKES TTVSPSYIAR VQEERDPGNE QGPIHGHGWL HAKQIKNKNH QGHKHGHGIG HGHQKPHGLG HGHQLKLDDL KQQREDGYDH RHPVGHGHGQ RHGHGHGHGH GRDKHTNKDK NNVKHTDQRR APLTSSSEDN TTSTQIQGRT EGFTLNPPLA QPAVISRGFQ DSGFTEGVIA TTSPYDTETH DDLIPDIHVQ PDSLSFKLIS DFPEATSHKC PGRPWKPVSR KDPTIETTEF SDFDLLDALS
3D Structure
ModBase 3D Structure for P08934
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Rat
Storage Buffer
Tris-based buffer, 50% glycerol
Tag Information
Tag type will be determined during the manufacturing process
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of Kng1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Kng1 recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for Kng1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
29.7kD
NCBI Official Full Name
kininogen-1 isoform 1
NCBI Official Synonym Full Names
kininogen 2-like 1
NCBI Official Symbol
Kng2l1  [Similar Products]
NCBI Official Synonym Symbols
Kng1; Kng2; Kngk; KINKG; KINKH; kininogen
  [Similar Products]
NCBI Protein Information
kininogen-1
UniProt Protein Name
Kininogen-1
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
NCBI Summary for Kng1
precursor protein of kinin which is found in plasma; cysteine protease inhibitor and a major acute phase reactant [RGD, Feb 2006]
UniProt Comments for Kng1
1 Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action); (5) LMW-kininogen inhibits the aggregation of thrombocytes; (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with Kng1 recombinant protein
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