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KRT18 cdna clone

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Catalog # MBS1265669
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
KRT18 cdna clone
Product Name

KRT18, cDNA Clone

Popular Item
Also Known As

KRT18 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
1293
Sequence
atgagcttca ccactcgctc caccttctcc accaactacc ggtccctggg ctctgtccag gcgcccagct acggcgcccg gccggtcagc agcgcggcca gcgtctatgc aggcgctggg ggctctggtt cccggatctc cgtgtcccgc tccaccagct tcaggggcgg catggggtcc gggggcctgg ccaccgggat agccgggggt ctggcaggaa tgggaggcat ccagaacgag aaggagacca tgcaaagcct gaacgaccgc ctggcctctt acctggacag agtgaggagc ctggagaccg agaaccggag gctggagagc aaaatccggg agcacttgga gaagaaggga ccccaggtca gagactggag ccattacttc aagatcatcg aggacctgag ggctcagatc ttcgcaaata ctgtggacaa tgcccgcatc gttctgcaga ttgacaatgc ccgtcttgct gctgatgact ttagagtcaa gtatgagaca gagctggcca tgcgccagtc tgtggagaac gacatccatg ggctccgcaa ggtcattgat gacaccaata tcacacgact gcagctggag acagagatcg aggctctcaa ggaggagctg ctcttcatga agaagaacca cgaagaggaa gtaaaaggcc tacaagccca gattgccagc tctgggttga ccgtggaggt agatgccccc aaatctcagg acctcgccaa gatcatggca gacatccggg cccaatatga cgagctggct cggaagaacc gagaggagct agacaagtac tggtctcagc agattgagga gagcaccaca gtggtcacca cacagtctgc tgaggttgga gctgctgaga cgacgctcac agagctgaga cgtacagtcc agtccttgga gatcgacctg gactccatga gaaatctgaa ggccagcttg gagaacagcc tgagggaggt ggaggcccgc tacgccctac agatggagca gctcaacggg atcctgctgc accttgagtc agagctggca cagacccggg cagagggaca gcgccaggcc caggagtatg aggccctgct gaacatcaag gtcaagctgg aggctgagat cgccacctac cgccgcctgc tggaagatgg cgaggacttt aatcttggtg atgccttgga cagcagcaac tccatgcaaa ccatccaaaa gaccaccacc cgccggatag tggatggcaa agtggtgtct gagaccaatg acaccaaagt tctgaggcat taa
OMIM
148070
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of KRT18 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for KRT18. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
48,058 Da
NCBI Official Full Name
Homo sapiens keratin 18, mRNA
NCBI Official Synonym Full Names
keratin 18
NCBI Official Symbol
KRT18  [Similar Products]
NCBI Official Synonym Symbols
K18; CK-18; CYK18
  [Similar Products]
NCBI Protein Information
keratin, type I cytoskeletal 18
UniProt Protein Name
Keratin, type I cytoskeletal 18
UniProt Synonym Protein Names
Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18
Protein Family
UniProt Gene Name
KRT18  [Similar Products]
UniProt Synonym Gene Names
CYK18; CK-18; K18  [Similar Products]
UniProt Entry Name
K1C18_HUMAN
NCBI Summary for KRT18
KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for KRT18
K18: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 18 and its filament partner keratin 8 are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Defects are a cause of cryptogenic cirrhosis.

Protein type: Nucleolus; Cytoskeletal

Chromosomal Location of Human Ortholog: 12q13

Cellular Component: cell-cell adherens junction; cytoplasm; intermediate filament; keratin filament; microtubule organizing center

Molecular Function: protein binding

Biological Process: anatomical structure morphogenesis; Golgi to plasma membrane CFTR protein transport; intermediate filament cytoskeleton organization and biogenesis; negative regulation of apoptosis

Disease: Cirrhosis, Familial
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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