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anti-KRT18 antibody :: anti-Human Keratin 18 Antibody

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Catalog # MBS854124
Unit / Price
  0.1 mg  /  $215 +1 FREE 8GB USB
Product Name

Keratin 18 (KRT18), Antibody

Full Product Name

Keratin 18 Antibody

Product Synonym Names
Keratin type I cytoskeletal 18; Cytokeratin-18; CK-18 K18
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P05783
Species Reactivity
Keratin 18 antibody detects endogenous levels of total Keratin 18 protein.
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
The antiserum was produced against synthesized peptide derived from human Keratin 18.
Preparation and Storage
Store at-20 degree C for 1 year
Other Notes
Small volumes of anti-KRT18 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-KRT18 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-KRT18 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:10000

Immunohistochemistry (IHC) of anti-KRT18 antibody
Peptide-+ Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Keratin 18 antibody.
anti-KRT18 antibody Immunohistochemistry (IHC) (IHC) image
Western Blot (WB) of anti-KRT18 antibody
Western blot analysis of extracts from HeLa cells, using Keratin 18 antibody.
anti-KRT18 antibody Western Blot (WB) (WB) image
Immunofluorescence (IF) of anti-KRT18 antibody
Peptide-+ Immunofluorescence analysis of HeLa cells, using Keratin 18 antibody.
anti-KRT18 antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for KRT18. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
48,058 Da
NCBI Official Full Name
keratin, type I cytoskeletal 18
NCBI Official Synonym Full Names
keratin 18
NCBI Official Symbol
KRT18  [Similar Products]
NCBI Official Synonym Symbols
K18; CK-18; CYK18
  [Similar Products]
NCBI Protein Information
keratin, type I cytoskeletal 18
UniProt Protein Name
Keratin, type I cytoskeletal 18
UniProt Synonym Protein Names
Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18
Protein Family
UniProt Gene Name
KRT18  [Similar Products]
UniProt Synonym Gene Names
CYK18; CK-18; K18  [Similar Products]
NCBI Summary for KRT18
KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for KRT18
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
Product References and Citations for anti-KRT18 antibody
Thomas M. Magin, J. Cell Biol., Mar 1998; 140: 1441. Carlos CaulĂ­n, J. Cell Biol., Sep 1997; 138: 1379. J Liao, J. Cell Biol., Dec 1995; 131: 1291. Nam-On Ku, J. Clin. Invest., Jan 1997; 99: 19.

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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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