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KYNURENINE elisa kit :: Human Kynurenine ELISA Kit

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Catalog # MBS033463
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KYNURENINE elisa kit
Product Name

Kynurenine, ELISA Kit

Popular Item
Full Product Name

Human Kynurenine ELISA Kit

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
MBS033463 COA
OMIM
610656
3D Structure
ModBase 3D Structure for Q6YP21
Species Reactivity
Specificity
No significant cross-reactivity or interference between this analyte and analogues is observed.
Samples
Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Assay Type
Sandwich
Detection Range
125 nmol/L - 4000 nmol/L.
Sensitivity
10 nmol/L.
Intra-assay Precision
Intra-assay CV (%) is less than 15%.
Inter-assay Precision
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of KYNURENINE elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for KYNURENINEpurchase
MBS033463 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Kynurenine, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing KYNURENINE. The ELISA analytical biochemical technique of the MBS033463 kit is based on KYNURENINE antibody-KYNURENINE antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect KYNURENINE antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, KYNURENINE. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Related Product Information for
KYNURENINE elisa kit
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of KYN (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS033463. Click to request current manual
NCBI/Uniprot data below describe general gene information for KYNURENINE. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
51,400 Da
NCBI Official Full Name
kynurenine--oxoglutarate transaminase 3 isoform 2
NCBI Official Synonym Full Names
cysteine conjugate-beta lyase 2
NCBI Official Symbol
CCBL2  [Similar Products]
NCBI Official Synonym Symbols
KAT3; KATIII
  [Similar Products]
NCBI Protein Information
kynurenine--oxoglutarate transaminase 3; RP11-82K18.3; kynurenine aminotransferase III; cysteine-S-conjugate beta-lyase 2; kynurenine--glyoxylate transaminase; kynurenine-oxoglutarate transaminase 3; kynurenine--oxoglutarate transaminase III
UniProt Protein Name
Kynurenine--oxoglutarate transaminase 3
UniProt Synonym Protein Names
Cysteine-S-conjugate beta-lyase 2 (EC:4.4.1.13); Kynurenine aminotransferase III; KATIII; Kynurenine--glyoxylate transaminase (EC:2.6.1.63); Kynurenine--oxoglutarate transaminase III
Protein Family
UniProt Gene Name
CCBL2  [Similar Products]
UniProt Synonym Gene Names
KAT3; KATIII  [Similar Products]
UniProt Entry Name
KAT3_HUMAN
NCBI Summary for KYNURENINE
This gene encodes an aminotransferase that transaminates kynurenine to form kynurenic acid. Kynurenic acid is a metabolite of tryptophan. Multiple alternatively spliced transcript variants that encode different proteins have been described for this gene. This gene shares 5' exon structure with the RNA binding motif protein, X-linked-like 1 locus on chromosome 1, but the coding sequences are non-overlapping. [provided by RefSeq, Jun 2009]
UniProt Comments for KYNURENINE
CCBL2: Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). May catalyze the beta-elimination of S-conjugates and Se- conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2- oxoglutarate as amino group acceptor (in vitro). Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.6.1.63; EC 4.4.1.13; Transferase; Lyase; EC 2.6.1.7

Chromosomal Location of Human Ortholog: 1p22.2

Cellular Component: mitochondrion

Molecular Function: cysteine-S-conjugate beta-lyase activity; protein homodimerization activity; kynurenine-glyoxylate transaminase activity; kynurenine-oxoglutarate transaminase activity; pyridoxal phosphate binding

Biological Process: amino acid metabolic process; biosynthetic process; tryptophan catabolic process; 2-oxoglutarate metabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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