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L3MBTL elisa kit :: Human l (3) mbt-like (Drosophila) ELISA Kit

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Catalog # MBS9337773
Unit / Price
  48-Strip-Wells  /  $470 +1 FREE 8GB USB
  96-Strip-Wells  /  $680 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
L3MBTL elisa kit
Product Name

l (3) mbt-like (Drosophila) (L3MBTL), ELISA Kit

Also Known As

Human Lethal, L3MBTL ELISA Kit

Product Synonym Names
Human Lethal (L3MBTL) ELISA kit; RP1-138B7.1; DKFZp586P1522; FLJ41181; H-L (3) MBT; KIAA0681; L3MBTL1; dJ138B7.3; l (3) mbt-like; lethal (3) malignant brain tumor l (3) ; l (3) mbt-like (Drosophila)
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
3D Structure
ModBase 3D Structure for Q9Y468
Species Reactivity
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of L3MBTL elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forL3MBTLpurchase
MBS9337773 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the l (3) mbt-like (Drosophila) (L3MBTL) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing L3MBTL. The ELISA analytical biochemical technique of the MBS9337773 kit is based on L3MBTL antibody-L3MBTL antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect L3MBTL antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, L3MBTL. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for L3MBTL. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
83,884 Da
NCBI Official Full Name
lethal(3)malignant brain tumor-like protein 1 isoform I
NCBI Official Synonym Full Names
l(3)mbt-like 1 (Drosophila)
NCBI Official Symbol
L3MBTL1  [Similar Products]
NCBI Official Synonym Symbols
L3MBTL; ZC2HC3; H-L(3)MBT; dJ138B7.3
  [Similar Products]
NCBI Protein Information
lethal(3)malignant brain tumor-like protein 1; lethal(3)malignant brain tumor-like protein 1; l(3)mbt protein homolog; lethal (3) malignant brain tumor l(3)
UniProt Protein Name
Lethal(3)malignant brain tumor-like protein 1
UniProt Synonym Protein Names
L(3)mbt protein homolog; L3MBTL1
UniProt Gene Name
L3MBTL1  [Similar Products]
UniProt Synonym Gene Names
KIAA0681; L3MBT; L3MBTL; H-l(3)mbt; H-l(3)mbt protein; L(3)mbt-like  [Similar Products]
UniProt Entry Name
NCBI Summary for L3MBTL
This gene represents a polycomb group gene. The encoded protein functions to regulate gene activity, likely via chromatin modification. The encoded protein may also be necessary for mitosis. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010]
UniProt Comments for L3MBTL
L3MBTL: Polycomb group (PcG) protein that specifically recognizes and binds mono- and dimethyllysine residues on target proteins, therey acting as a 'reader' of a network of post- translational modifications. PcG proteins maintain the transcriptionally repressive state of genes: acts as a chromatin compaction factor by recognizing and binding mono- and dimethylated histone H1b/HIST1H1E at 'Lys-26' (H1bK26me1 and H1bK26me2) and histone H4 at 'Lys-20' (H4K20me1 and H4K20me2), leading to condense chromatin and repress transcription. Recognizes and binds p53/TP53 monomethylated at 'Lys-382', leading to repress p53/TP53-target genes. Also recognizes and binds RB1/RB monomethylated at 'Lys-860'. Participates in the ETV6-mediated repression. Probably plays a role in cell proliferation. Overexpression induces multinucleated cells, suggesting that it is required to accomplish normal mitosis. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; Histone-binding

Chromosomal Location of Human Ortholog: 20q13.12

Cellular Component: nucleoplasm; plasma membrane; nucleolus; condensed chromosome; nucleus; chromatin

Molecular Function: identical protein binding; protein binding; nucleosomal histone binding; histone binding; zinc ion binding; nucleosome binding; SAM domain binding; chromatin binding; transcription factor activity; methylated histone residue binding

Biological Process: transcription, DNA-dependent; regulation of cell cycle; regulation of megakaryocyte differentiation; regulation of mitosis; hemopoiesis; chromatin modification; negative regulation of transcription, DNA-dependent
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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Organs/Tissues associated with L3MBTL elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >16 publications with L3MBTL and Brain
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