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anti-LAMA4 antibody :: anti-Human, Mouse LAMA4 Antibody

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Catalog # MBS855508
Unit / Price
  0.1 mg  /  $215 +1 FREE 8GB USB
Product Name

LAMA4, Antibody

Popular Item
Full Product Name

LAMA4 Antibody

Product Synonym Names
Laminin subunit alpha-4 [Precursor]; LAMA4
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
600133
3D Structure
ModBase 3D Structure for Q16363
Species Reactivity
Human, Mouse
Specificity
LAMA4 antibody detects endogenous levels of total LAMA4 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human LAMA4.
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-LAMA4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-LAMA4 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-LAMA4 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:40000

Testing Data of anti-LAMA4 antibody
Peptide-+
anti-LAMA4 antibody Testing Data image
Immunohistochemistry (IHC) of anti-LAMA4 antibody
Immunohistochemistry analysis of paraffin-embedded human heart tissue using LAMA4 antibody. Western blot analysis of extracts from COLO cells and 293 cells, using LAMA4 antibody.
anti-LAMA4 antibody Immunohistochemistry (IHC) (IHC) image
Immunofluorescence (IF) of anti-LAMA4 antibody
Peptide-+ Immunofluorescence analysis of NIH/3T3 cells, using LAMA4 antibody.
anti-LAMA4 antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for LAMA4. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
12,819 Da
NCBI Official Full Name
laminin subunit alpha-4 isoform 1
NCBI Official Synonym Full Names
laminin subunit alpha 4
NCBI Official Symbol
LAMA4  [Similar Products]
NCBI Official Synonym Symbols
LAMA3; CMD1JJ; LAMA4*-1
  [Similar Products]
NCBI Protein Information
laminin subunit alpha-4
UniProt Protein Name
Laminin subunit alpha-4
UniProt Synonym Protein Names
Laminin-14 subunit alpha; Laminin-8 subunit alpha; Laminin-9 subunit alpha
Protein Family
UniProt Gene Name
LAMA4  [Similar Products]
NCBI Summary for LAMA4
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the alpha chain isoform laminin, alpha 4. The domain structure of alpha 4 is similar to that of alpha 3, both of which resemble truncated versions of alpha 1 and alpha 2, in that approximately 1,200 residues at the N-terminus (domains IV, V and VI) have been lost. Laminin, alpha 4 contains the C-terminal G domain which distinguishes all alpha chains from the beta and gamma chains. The RNA analysis from adult and fetal tissues revealed developmental regulation of expression, however, the exact function of laminin, alpha 4 is not known. Tissue-specific utilization of alternative polyA-signal has been described in literature. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2011]
UniProt Comments for LAMA4
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.CautionGene LAMA4 was formerly called LAMA3.
Product References and Citations for anti-LAMA4 antibody
Iivanainen A., FEBS Lett. 365:183-188(1995). Richards A.J., Eur. J. Biochem. 238:813-821(1996). Mungall A.J., Nature 425:805-811(2003).

Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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Products associated withanti-LAMA4 antibody
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