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LAMP2 cdna clone

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Catalog # MBS1275848
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
LAMP2 cdna clone
Product Name

LAMP2, cDNA Clone

Popular Item
Also Known As

LAMP2 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
1233
Sequence
atggtgtgct tccgcctctt cccggttccg ggctcagggc tcgttctggt ctgcctagtc ctgggagctg tgcggtctta tgcattggaa cttaatttga cagattcaga aaatgccact tgcctttatg caaaatggca gatgaatttc acagttcgct atgaaactac aaataaaact tataaaactg taaccatttc agaccatggc actgtgacat ataatggaag catttgtggg gatgatcaga atggtcccaa aatagcagtg cagttcggac ctggcttttc ctggattgcg aattttacca aggcagcatc tacttattca attgacagcg tctcattttc ctacaacact ggtgataaca caacatttcc tgatgctgaa gataaaggaa ttcttactgt tgatgaactt ttggccatca gaattccatt gaatgacctt tttagatgca atagtttatc aactttggaa aagaatgatg ttgtccaaca ctactgggat gttcttgtac aagcttttgt ccaaaatggc acagtgagca caaatgagtt cctgtgtgat aaagacaaaa cttcaacagt ggcacccacc atacacacca ctgtgccatc tcctactaca acacctactc caaaggaaaa accagaagct ggaacctatt cagttaataa tggcaatgat acttgtctgc tggctaccat ggggctgcag ctgaacatca ctcaggataa ggttgcttca gttattaaca tcaaccccaa tacaactcac tccacaggca gctgccgttc tcacactgct ctacttagac tcaatagcag caccattaag tatctagact ttgtctttgc tgtgaaaaat gaaaaccgat tttatctgaa ggaagtgaac atcagcatgt atttggttaa tggctccgtt ttcagcattg caaataacaa tctcagctac tgggatgccc ccctgggaag ttcttatatg tgcaacaaag agcagactgt ttcagtgtct ggagcatttc agataaatac ctttgatcta agggttcagc ctttcaatgt gacacaagga aagtattcta cagcccaaga gtgttcgctg gatgatgaca ccattctaat cccaattata gttggtgctg gtctttcagg cttgattatc gttatagtga ttgcttacgt aattggcaga agaaaaagtt atgctggata tcagactctg taa
OMIM
300257
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of LAMP2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for LAMP2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
45,170 Da
NCBI Official Full Name
Homo sapiens lysosomal-associated membrane protein 2, mRNA
NCBI Official Synonym Full Names
lysosomal associated membrane protein 2
NCBI Official Symbol
LAMP2  [Similar Products]
NCBI Official Synonym Symbols
LAMPB; CD107b; LAMP-2; LGP110
  [Similar Products]
NCBI Protein Information
lysosome-associated membrane glycoprotein 2
UniProt Protein Name
Lysosome-associated membrane glycoprotein 2
UniProt Synonym Protein Names
CD107 antigen-like family member B; CD_antigen: CD107b
UniProt Gene Name
LAMP2  [Similar Products]
UniProt Synonym Gene Names
LAMP-2; Lysosome-associated membrane protein 2  [Similar Products]
UniProt Entry Name
LAMP2_HUMAN
NCBI Summary for LAMP2
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2008]
UniProt Comments for LAMP2
LAMP2: Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens. Defects in LAMP2 are the cause of Danon disease (DAND); also known as glycogen storage disease type 2B (GSD2B). DAND is a lysosomal glycogen storage disease characterized by the clinical triad of cardiomyopathy, vacuolar myopathy and mental retardation. It is often associated with an accumulation of glycogen in muscle and lysosomes. Belongs to the LAMP family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq24

Cellular Component: extracellular space; late endosome; late endosome membrane; lysosomal lumen; lysosomal membrane; lysosome; membrane; plasma membrane; platelet dense granule membrane

Molecular Function: enzyme binding; protein binding

Biological Process: platelet degranulation; protein import; protein stabilization; regulation of protein stability

Disease: Danon Disease
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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