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LBP elisa kit :: Mouse LBP ELISA Kit

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Catalog # MBS825103
Unit / Price
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  96 Tests  /  $470 +1 FREE 8GB USB
Typical Testing Data/Standard Curve (for reference only)
Product Name

LBP, ELISA Kit

Popular Item
Full Product Name

Mouse LBP ELISA Kit

Product Synonym Names
Lipopolysaccharide-binding protein; LBP
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
MBS825103 MSDS
3D Structure
ModBase 3D Structure for Q61805
Species Reactivity
Specificity
The Mouse LBP ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Mouse LBP proteins within the range of 1560 pg/ml - 100000 pg/ml.
Samples
Cell Culture Supernatants, Serum, Plasma.
Assay Type
Sandwich
Sensitivity
The minimum detectable dose of Mouse LBP is typically less than 50 pg/ml.
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of LBP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for LBPpurchase
MBS825103 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the LBP, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing LBP. The ELISA analytical biochemical technique of the MBS825103 kit is based on LBP antibody-LBP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LBP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LBP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Related Product Information for
LBP elisa kit
Principle of the Assay: Lipopolysaccharide binding protein is a protein that in humans is encoded by the LBP gene. This gene is mapped to 20q11.23. LBP is a soluble acute-phase protein that binds to bacterial lipopolysaccharide (or LPS) to elicit immune responses by presenting the LPS to important cell surface pattern recognition receptors called CD14 and TLR4. It is present in the cerebrospinal fluid of patients with pneumococcal meningitis. The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. LBP is made in the liver during the acute phase of infections and is thought to function as a carrier for LPS and to help control LPS-dependent monocyte responses.

Background/Introduction: Sandwich Enzyme-Linked Immunosorbent Assay for Quantitative Detection of Mouse LBP Concentrations in Cell Culture Supernatants, Serum, Plasma.
Applications Tested/Suitable for LBP elisa kit
Sandwich ELISA (SE)

Typical Testing Data/Standard Curve (for reference only) of LBP elisa kit

LBP elisa kit Typical Testing Data/Standard Curve (for reference only) image
Sample Manual Insert of MBS825103. Click to request current manual
NCBI/Uniprot data below describe general gene information for LBP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
53,055 Da
NCBI Official Full Name
lipopolysaccharide-binding protein
NCBI Official Synonym Full Names
lipopolysaccharide binding protein
NCBI Official Symbol
NCBI Official Synonym Symbols
Ly88; Bpifd2
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NCBI Protein Information
lipopolysaccharide-binding protein
UniProt Protein Name
Lipopolysaccharide-binding protein
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
LBP_MOUSE
UniProt Comments for LBP
LBP: Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. The LBP/LPS complex seems to interact with the CD14 receptor. Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular space; cell surface; extracellular region

Molecular Function: lipopolysaccharide binding; lipid binding; receptor binding

Biological Process: positive regulation of tumor necrosis factor biosynthetic process; immune system process; detection of molecule of bacterial origin; positive regulation of toll-like receptor 4 signaling pathway; positive regulation of interleukin-6 production; response to lipopolysaccharide; negative regulation of tumor necrosis factor production; positive regulation of tumor necrosis factor production; defense response to Gram-negative bacterium; lipid transport; leukocyte chemotaxis during inflammatory response; positive regulation of chemokine production; positive regulation of interleukin-8 production; lipopolysaccharide transport; defense response to Gram-positive bacterium; transport; macrophage activation during immune response; defense response to bacterium; acute-phase response; lipopolysaccharide-mediated signaling pathway; innate immune response; positive regulation of phagocytosis, engulfment; positive regulation of macrophage activation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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