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LCP1 recombinant protein :: Plastin-2 Recombinant Protein

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Catalog # MBS953535
Unit / Price
  0.01 mg (Yeast)  /  $110 +1 FREE 8GB USB
  0.01 mg (Baculovirus)  /  $120 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $190 +1 FREE 8GB USB
  0.1 mg (Yeast)  /  $285 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $460 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $750 +1 FREE 8GB USB
  0.05 mg (E-Coli)  /  $1,050 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,180 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $1,420 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,475 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,565 +1 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,220 +2 FREE 8GB USB
  1 mg (E-Coli)  /  $2,225 +2 FREE 8GB USB
SDS-Page
Product Name

Plastin-2 (LCP1), Recombinant Protein

Popular Item
Also Known As

Recombinant Human Plastin-2

Product Synonym Names
L-plastin; LC64P; Lymphocyte cytosolic protein 1; LCP-1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS953535 COA
Sequence Positions
2-627aa; Full Length
Sequence Length
627
Sequence
ARGSVSDEEM MELREAFAKV DTDGNGYISF NELNDLFKAA CLPLPGYRVR EITENLMATG DLDQDGRISF DEFIKIFHGL KSTDVAKTFR KAINKKEGIC AIGGTSEQSS VGTQHSYSEE EKYAFVNWIN KALENDPDCR HVIPMNPNTN DLFNAVGDGI VLCKMINLSV PDTIDERTIN KKKLTPFTIQ ENLNLALNSA SAIGCHVVNI GAEDLKEGKP YLVLGLLWQV IKIGLFADIE LSRNEALIAL LREGESLEDL MKLSPEELLL RWANYHLENA GCNKIGNFST DIKDSKAYYH LLEQVAPKGD EEGVPAVVID MSGLREKDDI QRAECMLQQA ERLGCRQFVT ATDVVRGNPK LNLAFIANLF NRYPALHKPE NQDIDWGALE GETREERTFR NWMNSLGVNP RVNHLYSDLS DALVIFQLYE KIKVPVDWNR VNKPPYPKLG GNMKKLENCN YAVELGKNQA KFSLVGIGGQ DLNEGNRTLT LALIWQLMRR YTLNILEEIG GGQKVNDDII VNWVNETLRE AKKSSSISSF KDPKISTSLP VLDLIDAIQP GSINYDLLKT ENLNDDEKLN NAKYAISMAR KIGARVYALP EDLVEVNPKM VMTVFACLMG KGMKRV
OMIM
153430
3D Structure
ModBase 3D Structure for P13796
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater than 90% as determined by SDS-PAGE. (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of LCP1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
LCP1 recombinant protein
Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69.
Product Categories/Family for LCP1 recombinant protein

LCP1 recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for LCP1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
86.1kD
NCBI Official Full Name
plastin-2
NCBI Official Synonym Full Names
lymphocyte cytosolic protein 1 (L-plastin)
NCBI Official Symbol
NCBI Official Synonym Symbols
LPL; CP64; PLS2; LC64P; HEL-S-37; L-PLASTIN
  [Similar Products]
NCBI Protein Information
plastin-2
UniProt Protein Name
Plastin-2
UniProt Synonym Protein Names
L-plastin; LC64P; Lymphocyte cytosolic protein 1; LCP-1
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
PLS2; LCP-1  [Similar Products]
UniProt Entry Name
PLSL_HUMAN
NCBI Summary for LCP1
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. [provided by RefSeq, Jul 2008]
UniProt Comments for LCP1
L-plastin: Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69. Monomer. Interacts with AIF1. Detected in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia, in spleen and other lymph node-containing organs. Expressed in peripheral blood T- lymphocytes, neutrophils, monocytes, B-lymphocytes, and myeloid cells.

Protein type: Motility/polarity/chemotaxis; Actin-binding

Chromosomal Location of Human Ortholog: 13q14.3

Cellular Component: actin cytoskeleton; actin filament; actin filament bundle; cytoplasm; cytosol; extracellular space; filopodium; focal adhesion; phagocytic cup; plasma membrane; podosome; ruffle; stress fiber

Molecular Function: actin binding; actin filament binding; calcium ion binding; GTPase binding; identical protein binding

Biological Process: actin filament bundle formation; cell migration; extracellular matrix disassembly; organ regeneration; regulation of intracellular protein transport; T cell activation during immune response
Product References and Citations for LCP1 recombinant protein
65-kilodalton protein phosphorylated by interleukin 2 stimulation bears two putative actin-binding sites and two calcium-binding sites.Zu Y., Shigesada K., Nishida E., Kubota I., Kohno M., Hanaoka M., Namba Y.Biochemistry 29:8319-8324(1990) Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S., Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.Nat. Genet. 36:40-45(2004) The DNA sequence and analysis of human chromosome 13.Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L., Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E., Griffiths-Jones S., Jones M.C., Keenan S.J., Oliver K., Scott C.E., Ainscough R., Almeida J.P., Ambrose K.D., Andrews D.T., Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Bannerjee R., Barlow K.F., Bates K., Beasley H., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P., Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M., Clegg S.C., Cobley V., Collins J.E., Corby N., Coville G.J., Deloukas P., Dhami P., Dunham I., Dunn M., Earthrowl M.E., Ellington A.G., Faulkner L., Frankish A.G., Frankland J., French L., Garner P., Garnett J., Gilbert J.G.R., Gilson C.J., Ghori J., Grafham D.V., Gribble S.M., Griffiths C., Hall R.E., Hammond S., Harley J.L., Hart E.A., Heath P.D., Howden P.J., Huckle E.J., Hunt P.J., Hunt A.R., Johnson C., Johnson D., Kay M., Kimberley A.M., King A., Laird G.K., Langford C.J., Lawlor S., Leongamornlert D.A., Lloyd D.M., Lloyd C., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S., Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K.M., Rice C.M., Searle S., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Steward C.A., Sycamore N., Tester J., Thomas D.W., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Wilming L., Wray P.W., Wright M.W., Young L., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Beck S., Bentley D.R., Rogers J., Ross M.T.Nature 428:522-528(2004)

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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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