{"id":168,"date":"2017-03-01T19:32:01","date_gmt":"2017-03-01T19:32:01","guid":{"rendered":"https:\/\/www.mybiosource.com\/learn\/?p=168"},"modified":"2023-03-07T16:40:14","modified_gmt":"2023-03-07T16:40:14","slug":"ucla-public-health-builds-hiv-risk-assessment-calculator","status":"publish","type":"post","link":"https:\/\/www.mybiosource.com\/learn\/ucla-public-health-builds-hiv-risk-assessment-calculator\/","title":{"rendered":"UCLA Public Health Builds HIV Risk Assessment Calculator"},"content":{"rendered":"<p style=\"padding-left: 200px;\"><strong><span style=\"text-decoration: underline;\">Table of Contents<\/span><\/strong><\/p>\n<p style=\"padding-left: 200px;\"><strong>1. Introduction: Pre-exposure prophylaxis (PrEP) for preventing HIV transmission during unprotected sex<\/strong><br \/>\n<strong>2. CDC guidelines for PrEP and the gaps in the guidelines<\/strong><br \/>\n<strong>3. UCLA study and recommendations for filling the gaps in CDC guidelines<\/strong><br \/>\n<strong>4. Development of an online risk assessment calculator <\/strong><br \/>\n<strong>5. HIV-risk algorithm for recommending PrEP to clients at the center<\/strong><br \/>\n<strong>6. Conclusion<\/strong><\/p>\n<hr \/>\n<p>Pre-exposure prophylaxis (<span id=\"urn:enhancement-23f32605-1acf-4d8f-9ccf-449746a637e7\" class=\"textannotation disambiguated wl-thing\" itemid=\"https:\/\/data.wordlift.io\/wl1503301\/entity\/prep\">PrEP<\/span>) is currently used as a measure that in preventing <span id=\"urn:enhancement-a54405f1-bbca-4b8d-b9cf-a9862ccb19b1\" class=\"textannotation disambiguated wl-thing\" itemid=\"https:\/\/data.wordlift.io\/wl1503301\/entity\/hiv\">HIV<\/span> transmission during unprotected sex. Though not foolproof, studies have shown taking daily doses of tenofovir the drug reduces the risk by 92% in preventing <span id=\"urn:enhancement-fa79a5c3-0dec-434a-91cd-3aa569c83011\" class=\"textannotation disambiguated wl-thing\" itemid=\"https:\/\/data.wordlift.io\/wl1503301\/entity\/hiv\">HIV<\/span> infection.<img loading=\"lazy\" decoding=\"async\" class=\"alignright size-medium wp-image-170\" src=\"https:\/\/www.mybiosource.com\/learn\/wp-content\/uploads\/2017\/03\/virus-hiv-300x300.jpg\" alt=\"\" width=\"300\" height=\"300\" srcset=\"https:\/\/www.mybiosource.com\/learn\/wp-content\/uploads\/2017\/03\/virus-hiv-300x300.jpg 300w, https:\/\/www.mybiosource.com\/learn\/wp-content\/uploads\/2017\/03\/virus-hiv-150x150.jpg 150w, https:\/\/www.mybiosource.com\/learn\/wp-content\/uploads\/2017\/03\/virus-hiv-768x768.jpg 768w, https:\/\/www.mybiosource.com\/learn\/wp-content\/uploads\/2017\/03\/virus-hiv-1024x1024.jpg 1024w, https:\/\/www.mybiosource.com\/learn\/wp-content\/uploads\/2017\/03\/virus-hiv-370x370.jpg 370w, https:\/\/www.mybiosource.com\/learn\/wp-content\/uploads\/2017\/03\/virus-hiv-570x570.jpg 570w, https:\/\/www.mybiosource.com\/learn\/wp-content\/uploads\/2017\/03\/virus-hiv-770x770.jpg 770w, https:\/\/www.mybiosource.com\/learn\/wp-content\/uploads\/2017\/03\/virus-hiv-580x580.jpg 580w, https:\/\/www.mybiosource.com\/learn\/wp-content\/uploads\/2017\/03\/virus-hiv.jpg 1100w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/p>\n<p>Since 2012, <span id=\"urn:enhancement-245814fc-1fd7-4bab-8fce-32b6030e397c\" class=\"textannotation disambiguated wl-organization\" itemid=\"https:\/\/data.wordlift.io\/wl1503301\/entity\/centers-for-disease-control-and-prevention\">CDC<\/span> has recommended <span id=\"urn:enhancement-1d97ce53-81f3-4381-926b-fc08411530b4\" class=\"textannotation disambiguated wl-thing\" itemid=\"https:\/\/data.wordlift.io\/wl1503301\/entity\/prep\">PrEP<\/span> for homosexual, bisexual men and for men who were in relationship with <span id=\"urn:enhancement-c83be2ea-67d7-41ed-b294-6662ff42ba4e\" class=\"textannotation disambiguated wl-thing\" itemid=\"https:\/\/data.wordlift.io\/wl1503301\/entity\/hiv\">HIV<\/span>-positive partners. However, UCLA Fielding School of Public Health suggested changes in the recommendations provided by <span id=\"urn:enhancement-6c5987a3-6693-4175-9fe4-634a0ad812bf\" class=\"textannotation disambiguated wl-organization\" itemid=\"https:\/\/data.wordlift.io\/wl1503301\/entity\/centers-for-disease-control-and-prevention\">CDC<\/span>, primarily filling the existing gaps in guidelines drafted by <span id=\"urn:enhancement-9dd404e9-063a-42cf-9f74-c81e5491d00a\" class=\"textannotation disambiguated wl-organization\" itemid=\"https:\/\/data.wordlift.io\/wl1503301\/entity\/centers-for-disease-control-and-prevention\">CDC<\/span>.<\/p>\n<p>The UCLA research group suggested changes in the federal guidelines established by <span id=\"urn:enhancement-7af8267b-c1ea-4886-9185-ba4c0005a3e1\" class=\"textannotation disambiguated wl-organization\" itemid=\"https:\/\/data.wordlift.io\/wl1503301\/entity\/centers-for-disease-control-and-prevention\">CDC<\/span> after carrying out an extensive study in collaboration with Los Angeles LGBT Center. The researchers feel the guidelines established by <span id=\"urn:enhancement-d3e8182d-cd2b-4c80-938e-f5f8a0ce8b18\" class=\"textannotation disambiguated wl-organization\" itemid=\"https:\/\/data.wordlift.io\/wl1503301\/entity\/centers-for-disease-control-and-prevention\">CDC<\/span> omit important characteristics related to sexual behavior, and therefore someone might be at higher risk of <span id=\"urn:enhancement-6ba6170f-11d0-41af-aa19-89cafff00cfb\" class=\"textannotation disambiguated wl-thing\" itemid=\"https:\/\/data.wordlift.io\/wl1503301\/entity\/infection\">infection<\/span>. Also, the group developed an online risk assessment calculator based on their findings that could fill the gap in recommendations.<\/p>\n<p>The co-author of the study and a professor of biostatistics, Robert Weis said, \u201cTo the best of our knowledge, this <span id=\"urn:enhancement-7adc3d41-5511-4689-a44e-3addbd2e22b6\" class=\"textannotation disambiguated wl-thing\" itemid=\"https:\/\/data.wordlift.io\/wl1503301\/entity\/prep\">PrEP<\/span> Calculator is the first of its kind to be based on real-world data.\u201d He also said the calculator helps the users with the risk assessment to make informed decisions.<\/p>\n<p>The study was carried out with the help of The Los Angeles LGBT Center which is one of the largest <span id=\"urn:enhancement-d2bde23e-979b-4d73-90da-3fe3d30ac291\" class=\"textannotation disambiguated wl-thing\" itemid=\"https:\/\/data.wordlift.io\/wl1503301\/entity\/hiv\">HIV<\/span> testing providers in Los Angeles County for LGBT community. The center serves nearly 13K people in a year. The UCLA team collected data on behavioral risk factors for <span id=\"urn:enhancement-7baf0d83-bf66-4855-9392-3ba93d96a932\" class=\"textannotation disambiguated wl-thing\" itemid=\"https:\/\/data.wordlift.io\/wl1503301\/entity\/hiv\">HIV<\/span> among clients at each visit and what characteristics distinguished men who have sex with men, who were <span id=\"urn:enhancement-f2280d63-8864-4164-9bbc-4048d445e37c\" class=\"textannotation disambiguated wl-thing\" itemid=\"https:\/\/data.wordlift.io\/wl1503301\/entity\/hiv\">HIV<\/span>-negative throughout testing and from people who subsequently tested positive for <span id=\"urn:enhancement-97ef68f5-d2b5-488d-884e-1bb2ff0f186e\" class=\"textannotation disambiguated wl-thing\" itemid=\"https:\/\/data.wordlift.io\/wl1503301\/entity\/hiv\">HIV<\/span>.<\/p>\n<p>Using this data on behavior amounting to sex only, the researchers built an <span id=\"urn:enhancement-0795e29d-1962-4352-89c5-eebc448d8418\" class=\"textannotation disambiguated wl-thing\" itemid=\"https:\/\/data.wordlift.io\/wl1503301\/entity\/hiv\">HIV<\/span>-risk algorithm, a mechanism for recommending <span id=\"urn:enhancement-c71ad0b4-33af-461b-84d0-21e4823ef578\" class=\"textannotation disambiguated wl-thing\" itemid=\"https:\/\/data.wordlift.io\/wl1503301\/entity\/prep\">PrEP<\/span> to clients in the center. The data collected for the study included questions on the subject of substance use, the number of sex partners, age, partner level data and race or ethnicity.<\/p>\n<p>The researchers also noted that when individuals with a risk score of greater than 5 was asked to use the calculator, 75% of <span id=\"urn:enhancement-dddaabce-9ecd-4cd4-8d20-76d5635788b9\" class=\"textannotation disambiguated wl-thing\" itemid=\"https:\/\/data.wordlift.io\/wl1503301\/entity\/hiv\">HIV<\/span> infections were averted assessed through follow-up testing. The calculator aided in the effective use of <span id=\"urn:enhancement-02d78794-090c-4dc0-b826-64d71eb8adbe\" class=\"textannotation disambiguated wl-thing\" itemid=\"https:\/\/data.wordlift.io\/wl1503301\/entity\/prep\">PrEP<\/span>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Table of Contents 1. Introduction: Pre-exposure prophylaxis (PrEP) for preventing HIV transmission during unprotected sex 2. CDC guidelines for PrEP and the gaps in the guidelines 3. UCLA study and recommendations for filling the gaps in CDC guidelines 4. Development of an online risk assessment calculator 5. HIV-risk algorithm for recommending PrEP to clients at [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":169,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[2],"tags":[],"class_list":["post-168","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-outbreaks"],"_links":{"self":[{"href":"https:\/\/www.mybiosource.com\/learn\/wp-json\/wp\/v2\/posts\/168","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.mybiosource.com\/learn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.mybiosource.com\/learn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.mybiosource.com\/learn\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.mybiosource.com\/learn\/wp-json\/wp\/v2\/comments?post=168"}],"version-history":[{"count":0,"href":"https:\/\/www.mybiosource.com\/learn\/wp-json\/wp\/v2\/posts\/168\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.mybiosource.com\/learn\/wp-json\/wp\/v2\/media\/169"}],"wp:attachment":[{"href":"https:\/\/www.mybiosource.com\/learn\/wp-json\/wp\/v2\/media?parent=168"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.mybiosource.com\/learn\/wp-json\/wp\/v2\/categories?post=168"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.mybiosource.com\/learn\/wp-json\/wp\/v2\/tags?post=168"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}