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LGMN elisa kit :: Human Legumain (LGMN) ELISA Kit

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Catalog # MBS451078
Unit / Price
  48-Strip-Wells  /  $400 +1 FREE 8GB USB
  96-Strip-Wells  /  $535 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $2,425 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $4,710 +5 FREE 8GB USB
Typical Testing Data/Standard Curve (for reference only)
Product Name

Legumain (LGMN), ELISA Kit

Popular Item
Full Product Name

Human Legumain (LGMN) ELISA Kit

Product Synonym Names
AEP; LGMN1; PRSC1; Protease,Cysteine 1; Asparaginyl endopeptidase
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
MBS451078 COA
OMIM
Y09862 mRNA
3D Structure
ModBase 3D Structure for Q99538
Species Reactivity
Samples
Serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Assay Type
Sandwich
Detection Range
0.312-20ng/mL
Sensitivity
0.118ng/mL
Intra Assay
CV<10%
Inter Assay
CV<12%
Preparation and Storage
For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of LGMN elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forLGMNpurchase
MBS451078 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Legumain (LGMN) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing LGMN. The ELISA analytical biochemical technique of the MBS451078 kit is based on LGMN antibody-LGMN antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LGMN antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LGMN. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Typical Testing Data/Standard Curve (for reference only) of LGMN elisa kit
LGMN elisa kit Typical Testing Data/Standard Curve (for reference only) image
Sample Manual Insert of MBS451078. Click to request current manual
NCBI/Uniprot data below describe general gene information for LGMN. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
42,008 Da
NCBI Official Full Name
legumain preproprotein
NCBI Official Synonym Full Names
legumain
NCBI Official Symbol
NCBI Official Synonym Symbols
AEP; LGMN1; PRSC1
  [Similar Products]
NCBI Protein Information
legumain
UniProt Protein Name
Legumain
UniProt Synonym Protein Names
Asparaginyl endopeptidase; Protease, cysteine 1
UniProt Gene Name
UniProt Synonym Gene Names
PRSC1  [Similar Products]
NCBI Summary for LGMN
This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq, Jul 2008]
UniProt Comments for LGMN
Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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