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LMBR1 elisa kit :: Human limb region 1 homolog (mouse) ELISA Kit

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Catalog # MBS9320329
Unit / Price
  48-Strip-Wells  /  $470 +1 FREE 8GB USB
  96-Strip-Wells  /  $680 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
LMBR1 elisa kit
Product Name

limb region 1 homolog (mouse) (LMBR1), ELISA Kit

Also Known As

Human Limb region 1 protein homolog, LMBR1 ELISA Kit

Product Synonym Names
Human Limb region 1 protein homolog (LMBR1) ELISA kit; ACHP; C7orf2; DIF14; FLJ11665; PPD2; TPT; differentiation-related gene 14; limb region 1 protein; limb region 1 homolog (mouse)
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
605522
3D Structure
ModBase 3D Structure for Q8WVP7
Species Reactivity
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of LMBR1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forLMBR1purchase
MBS9320329 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the limb region 1 homolog (mouse) (LMBR1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing LMBR1. The ELISA analytical biochemical technique of the MBS9320329 kit is based on LMBR1 antibody-LMBR1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LMBR1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LMBR1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for LMBR1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
55,098 Da
NCBI Official Full Name
limb region 1 protein homolog
NCBI Official Synonym Full Names
limb development membrane protein 1
NCBI Official Symbol
LMBR1  [Similar Products]
NCBI Official Synonym Symbols
TPT; ZRS; ACHP; PPD2; DIF14; C7orf2
  [Similar Products]
NCBI Protein Information
limb region 1 protein homolog; limb region 1 homolog; differentiation-related gene 14 protein
UniProt Protein Name
Limb region 1 protein homolog
UniProt Synonym Protein Names
Differentiation-related gene 14 protein
Protein Family
UniProt Gene Name
LMBR1  [Similar Products]
UniProt Synonym Gene Names
C7orf2; DIF14  [Similar Products]
UniProt Entry Name
LMBR1_HUMAN
NCBI Summary for LMBR1
This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression. [provided by RefSeq, Jul 2008]
UniProt Comments for LMBR1
LMBR1: Putative membrane receptor. Defects in LMBR1 are associated with preaxial polydactyly type 2 (PPD2); also known as polydactyly of triphalangeal thumb. Polydactyly consists of duplication of the distal phalanx. The thumb in PPD2 is usually opposable and possesses a normal metacarpal. The mutations do not change the normal expression of LMBR1, but alter the expression of SHH by disrupting a long-range, cis-regulatory element of that gene. Defects in LMBR1 are the cause of acheiropody (ACHP). Acheiropody is a very rare condition characterized by bilateral congenital amputations of the hands and feet. The specific malformative phenotype consists of a complete amputation of the distal epiphysis of the humerus, amputation of the tibial diaphysis, and aplasia of the radius, ulna, fibula, and of all the bones of the hands and feet. This syndrome of autosomal recessive inheritance has only been observed in Brazil so far. Defects in LMBR1 are a cause of syndactyly type 4 (SDTY4). SDTY4 is a very rare congenital distal limb malformation characterized by complete bilateral syndactyly (involving all digits 1 to 5). A frequent association with polydactyly (with six metacarpals and six digits) has been reported. Feet are affected occasionally. The condition is inherited as an autosomal dominant trait. Belongs to the LIMR family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 7q36

Cellular Component: integral to membrane

Biological Process: embryonic digit morphogenesis

Disease: Syndactyly, Type Iv; Laurin-sandrow Syndrome; Polydactyly, Preaxial Ii; Tibia, Hypoplasia Or Aplasia Of, With Polydactyly; Acheiropody
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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