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LMX1A cdna clone

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Catalog # MBS1269750
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
LMX1A cdna clone
Product Name

LMX1A, cDNA Clone

Popular Item
Also Known As

LMX1A cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
303
Sequence
atggaaggaa tcatgaaccc ctacacggct ctgcccaccc cacagcagct cctggccatc gagcagagtg tctacagctc agatcccttc cgacagggtc tcaccccacc ccagatgcct ggagaccaca tgcaccctta tggtgccgag ccccttttcc atgacctgga tagcgacgac acctccctca gtaacctggg tgactgtttc ctagcaacct cagaagctgg gcctctgcag tccagagtgg gaaaccccat tgaccatctg tactccatgc agaattctta cttcacatct tga
OMIM
600298
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of LMX1A cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for LMX1A. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
14,615 Da
NCBI Official Full Name
Homo sapiens LIM homeobox transcription factor 1, alpha, mRNA
NCBI Official Synonym Full Names
LIM homeobox transcription factor 1 alpha
NCBI Official Symbol
LMX1A  [Similar Products]
NCBI Official Synonym Symbols
LMX1; LMX1.1
  [Similar Products]
NCBI Protein Information
LIM homeobox transcription factor 1-alpha
UniProt Protein Name
LIM homeobox transcription factor 1-alpha
UniProt Synonym Protein Names
LIM/homeobox protein 1.1; LMX-1.1; LIM/homeobox protein LMX1A
UniProt Gene Name
LMX1A  [Similar Products]
UniProt Synonym Gene Names
LMX-1.1  [Similar Products]
UniProt Entry Name
LMX1A_HUMAN
NCBI Summary for LMX1A
This gene encodes a homeodomain and LIM-domain containing protein. The encoded protein is a transcription factor that acts as a positive regulator of insulin gene transcription. This gene also plays a role in the development of dopamine producing neurons during embryogenesis. Mutations in this gene are associated with an increased risk of developing Parkinson's disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
UniProt Comments for LMX1A
LMX1A: Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Cell development/differentiation; Motility/polarity/chemotaxis; Transcription factor

Chromosomal Location of Human Ortholog: 1q24.1

Molecular Function: protein binding

Biological Process: positive regulation of transcription from RNA polymerase II promoter
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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