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LNPEP elisa kit :: Human Leucyl-Cystinyl Aminopeptidase ELISA Kit

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Catalog # MBS007258
Unit / Price
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  48-Strip-Wells  /  $470 +1 FREE 8GB USB
  96-Strip-Wells  /  $680 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
LNPEP elisa kit
Product Name

Leucyl-Cystinyl Aminopeptidase (LNPEP), ELISA Kit

Full Product Name

Human Leucyl-Cystinyl Aminopeptidase ELISA Kit

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Chromosome Location
Chromosome: 5; NC_000005.9 (96271346..96365115). Location: 5q15
OMIM
151300
3D Structure
ModBase 3D Structure for Q9UIQ6
Species Reactivity
Assay Type
Sandwich
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of LNPEP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for LNPEPpurchase
MBS007258 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Leucyl-Cystinyl Aminopeptidase (LNPEP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing LNPEP. The ELISA analytical biochemical technique of the MBS007258 kit is based on LNPEP antibody-LNPEP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LNPEP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LNPEP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for LNPEP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
117,349 Da
NCBI Official Full Name
leucyl-cystinyl aminopeptidase isoform 1
NCBI Official Synonym Full Names
leucyl/cystinyl aminopeptidase
NCBI Official Symbol
LNPEP  [Similar Products]
NCBI Official Synonym Symbols
CAP; IRAP; PLAP; P-LAP
  [Similar Products]
NCBI Protein Information
leucyl-cystinyl aminopeptidase; otase; oxytocinase; vasopressinase; AT (4) receptor; angiotensin IV receptor; insulin-regulated aminopeptidase; placental leucine aminopeptidase; insulin-responsive aminopeptidase; insulin-regulated membrane aminopeptidase
UniProt Protein Name
Leucyl-cystinyl aminopeptidase
UniProt Synonym Protein Names
Insulin-regulated membrane aminopeptidase; Insulin-responsive aminopeptidase; IRAP; Oxytocinase; OTase; Placental leucine aminopeptidase
UniProt Gene Name
LNPEP  [Similar Products]
UniProt Synonym Gene Names
OTASE; Cystinyl aminopeptidase; IRAP; OTase; P-LAP  [Similar Products]
UniProt Entry Name
LCAP_HUMAN
NCBI Summary for LNPEP
This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
UniProt Comments for LNPEP
IRAP: a leucyl/cystinyl aminopeptidase. A type II membrane protein and secreted. Resides in intracellular vesicles together with GLUT4 and can then translocate to the cell surface in response to insulin and/or oxytocin. Degrades peptide hormones such as oxytocin, vasopressin and angiotensin III, and plays a role in maintaining homeostasis during pregnancy. May be involved in the inactivation of neuronal peptides in the brain. Cleaves Met-enkephalin and dynorphin. Binds angiotensin IV and may be the angiotensin IV receptor in the brain. Three alternatively spliced isoforms have been described.

Protein type: EC 3.4.11.3; Protease; Membrane protein, integral

Chromosomal Location of Human Ortholog: 5q15

Cellular Component: cytoplasmic vesicle membrane; membrane; perinuclear region of cytoplasm; lysosomal membrane; integral to plasma membrane; extracellular region; plasma membrane; intracellular; cytosol

Molecular Function: zinc ion binding; metallopeptidase activity; aminopeptidase activity

Biological Process: antigen processing and presentation of peptide antigen via MHC class I; protein polyubiquitination; cell-cell signaling; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; antigen processing and presentation of exogenous peptide antigen via MHC class I; protein catabolic process; female pregnancy; proteolysis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with LNPEP elisa kit
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