P0C1Q3.1
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
59,829 Da
NCBI Official Full Name
Lysophosphatidylcholine acyltransferase 2
NCBI Official Synonym Full Names
lysophosphatidylcholine acyltransferase 2
NCBI Protein Information
lysophosphatidylcholine acyltransferase 2; lysoPAFAT; 1-AGPAT 11; LPC acyltransferase 2; 1-AGP acyltransferase 11; acyltransferase-like 1-A; lysoPC acyltransferase 2; acetyl-CoA:lyso-PAF acetyltransferase; 1-acylglycerophosphocholine O-acyltransferase; 1-acylglycerol-3-phosphate O-acyltransferase 11; 1-alkylglycerophosphocholine O-acetyltransferase; acetyl-CoA:lyso-platelet-activating factor acetyltransferase
UniProt Protein Name
Lysophosphatidylcholine acyltransferase 2
UniProt Synonym Protein Names
1-acylglycerol-3-phosphate O-acyltransferase 11 (EC:2.3.1.51); 1-AGP acyltransferase 11; 1-AGPAT 11; 1-acylglycerophosphocholine O-acyltransferase; 1-alkylglycerophosphocholine O-acetyltransferase (EC:2.3.1.67); Acetyl-CoA:lyso-platelet-activating factor acetyltransferase; Acetyl-CoA:lyso-PAF acetyltransferase; Lyso-PAF acetyltransferase; LysoPAFAT; Acyltransferase-like 1
UniProt Synonym Gene Names
Aytl1; Aytl1a; Lpcat2a; LPC acyltransferase 2; LPCAT-2; LysoPC acyltransferase 2; 1-AGP acyltransferase 11; 1-AGPAT 11; Acetyl-CoA:lyso-PAF acetyltransferase; Lyso-PAF acetyltransferase; LysoPAFAT [Similar Products]
UniProt Entry Name
PCAT2_RAT
UniProt Comments for Lpcat2
Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). Also converts lyso-PAF to 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases. Also catalyzes the conversion of 1-acyl-sn-glycero-3-phosphocholine to 1,2-diacyl-sn-glycero-3-phosphocholine. Involved in the regulation of lipid droplet number and size.
Research Articles on Lpcat2
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Products associated with Lpcat2 recombinant protein
Pathways associated with Lpcat2 recombinant protein
Organs/Tissues associated with Lpcat2 recombinant protein
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