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LPIN3 elisa kit :: Human lipin 3 ELISA Kit

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Catalog # MBS9342180
Unit / Price
  48-Strip-Wells  /  $470 +1 FREE 8GB USB
  96-Strip-Wells  /  $680 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
LPIN3 elisa kit
Product Name

lipin 3 (LPIN3), ELISA Kit

Full Product Name

Human Phosphatidate phosphatase LPIN3, LPIN3 ELISA Kit

Product Synonym Names
Human Phosphatidate phosphatase LPIN3 (LPIN3) ELISA kit; RP4-620E11.3; LIPN3L; SMP2; dJ450M14.2; dJ450M14.3; dJ620E11.2; lipin 3-like; lipin 3
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
605520
3D Structure
ModBase 3D Structure for Q9BQK8
Species Reactivity
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of LPIN3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forLPIN3purchase
MBS9342180 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the lipin 3 (LPIN3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing LPIN3. The ELISA analytical biochemical technique of the MBS9342180 kit is based on LPIN3 antibody-LPIN3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LPIN3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LPIN3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for LPIN3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
93,614 Da
NCBI Official Full Name
phosphatidate phosphatase LPIN3
NCBI Official Synonym Full Names
lipin 3
NCBI Official Symbol
LPIN3  [Similar Products]
NCBI Official Synonym Symbols
SMP2; LIPN3L; dJ450M14.2; dJ450M14.3; dJ620E11.2
  [Similar Products]
NCBI Protein Information
phosphatidate phosphatase LPIN3; lipin-3
UniProt Protein Name
Phosphatidate phosphatase LPIN3
UniProt Synonym Protein Names
Lipin-3; Lipin-3-like
Protein Family
UniProt Gene Name
LPIN3  [Similar Products]
UniProt Synonym Gene Names
LIPN3L  [Similar Products]
UniProt Entry Name
LPIN3_HUMAN
NCBI Summary for LPIN3
Humans lipodystrophy is characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. Mice carrying mutations in the fatty liver dystrophy (fld) gene have similar phenotypes. Through positional cloning, the mouse gene responsible for fatty liver dystrophy was isolated and designated Lpin1. The nuclear protein encoded by Lpin1 was named lipin. Lpin1 mRNA was expressed at high levels in adipose tissue and was induced during differentiation of preadipocytes. These results indicated that lipin is required for normal adipose tissue development and provided a candidate gene for human lipodystrophy. Through database searches, mouse and human EST and genomic sequences with similarities to Lpin1 were identified. These included two related mouse genes (Lpin2 and Lpin3) and three human homologs (LPIN1, LPIN2, and LPIN3). Human LPIN1 gene has been mapped to 2p25.; linkages of fat mass and serum leptin levels to this same region have been noted. Human LPIN2 and LPIN3 mapped to chromosomes 18p11 and 20q11-q12, respectively. The mouse genes encoding Lpin1, Lpin2, and Lpin3 mapped to chromosome 12, 17, and 2, respectively. [provided by RefSeq, Jul 2008]
UniProt Comments for LPIN3
LPIN3: Regulates fatty acid metabolism. Magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis. Belongs to the lipin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.3.4

Chromosomal Location of Human Ortholog: 20q12

Cellular Component: endoplasmic reticulum membrane; nucleus

Molecular Function: phosphatidate phosphatase activity; transcription coactivator activity

Biological Process: dephosphorylation; phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidylethanolamine biosynthetic process; phosphatidylcholine biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; triacylglycerol biosynthetic process; fatty acid catabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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