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LRRFIP1 cdna clone

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Catalog # MBS1270649
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
LRRFIP1 cdna clone
Product Name

LRRFIP1, cDNA Clone

Popular Item
Also Known As

LRRFIP1 cDNA Clone

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
318
Sequence
atgcatgtaa tggacctaca aagggatgcc aacagacaga tcagcgacct caaatttaaa cttgcaaaat ctgagcaaga gataactgca ttagaacaaa atgtaataag gttagagagt caagtatcac gttacaaatc agcggctgaa aatgcagaaa aaatagaaga tgaacttaag gcagaaaaac ggaaactcca aagagagctc cgctctgcat tggataaaac agaagagctc gaggtgagca acggccactt agtgaagcgt ctggaaaaaa tgaaagcaaa tcggagtgca ctcttgtccc agcagtaa
OMIM
603256
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of LRRFIP1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for LRRFIP1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
73,060 Da
NCBI Official Full Name
Homo sapiens leucine rich repeat (in FLII) interacting protein 1, mRNA
NCBI Official Synonym Full Names
LRR binding FLII interacting protein 1
NCBI Official Symbol
LRRFIP1  [Similar Products]
NCBI Official Synonym Symbols
GCF2; TRIP; FLAP1; GCF-2; FLAP-1; HUFI-1; FLIIAP1
  [Similar Products]
NCBI Protein Information
leucine-rich repeat flightless-interacting protein 1
UniProt Protein Name
Leucine-rich repeat flightless-interacting protein 1
UniProt Synonym Protein Names
GC-binding factor 2; TAR RNA-interacting protein
UniProt Gene Name
LRRFIP1  [Similar Products]
UniProt Synonym Gene Names
GCF2; TRIP; LRR FLII-interacting protein 1  [Similar Products]
UniProt Entry Name
LRRF1_HUMAN
UniProt Comments for LRRFIP1
LRRFIP1: Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. Belongs to the LRRFIP family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; RNA-binding

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: cell-cell adherens junction; cytoplasm; cytoskeleton; cytosol; plasma membrane

Molecular Function: DNA binding; double-stranded RNA binding; protein binding; protein homodimerization activity

Biological Process: positive regulation of interferon type I production; regulation of transcription from RNA polymerase II promoter
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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