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LRRFIP1 recombinant protein :: Leucine-rich repeat flightless-interacting protein 1 Recombinant Protein

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Catalog # MBS1265458
Unit / Price
  0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
  0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
  0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $855 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $990 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,145 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,235 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,255 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,300 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,805 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $1,875 +2 FREE 8GB USB
  1 mg (Yeast)  /  $1,970 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,400 +3 FREE 8GB USB
SDS-PAGE
Product Name

Leucine-rich repeat flightless-interacting protein 1 (LRRFIP1), Recombinant Protein

Popular Item
Also Known As

Recombinant human Leucine-rich repeat flightless-interacting protein 1

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-314aa; Partial of Isoform 3
Sequence
MTSPAAAQSR EIDCLSPEAQ KLAEARLAAK RAARAEAREI RMKELERQQK EVEERPEKDF TEKGSRNMPG LSAATLASLG GTSSRRGSGD TSISIDTEAS IREIKDSLAE VEEKYKKAMV SNAQLDNEKT NFMYQVDTLK DMLLELEEQL AESRRQYEEK NKEFEREKHA HSILQFQFAE VKEALKQREE MLEKHGIILN SEIATNGETS DTLNNVGYQG PTKMTKEELN ALKSTGDGTL GRASEVEVKN EIVANVGKRE ILHNTEKEQH TEDTVKDCVD IEVFPAGENT EDQKSSEDTA PFLGTLAGAT YEEQSLSTCS LDR
Chromosome Location
Chromosome: 2; NC_000002.11 (238536224..238690290). Location: 2q37.3
OMIM
603256
3D Structure
ModBase 3D Structure for Q32MZ4
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Preparation and Storage
Store at -20 degree C. For extended storage, conserve at -20 or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of LRRFIP1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
LRRFIP1 recombinant protein
Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
Product Categories/Family for LRRFIP1 recombinant protein

LRRFIP1 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for LRRFIP1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
89,253 Da[Similar Products]
NCBI Official Full Name
leucine-rich repeat flightless-interacting protein 1 isoform 1
NCBI Official Synonym Full Names
leucine rich repeat (in FLII) interacting protein 1
NCBI Official Symbol
LRRFIP1  [Similar Products]
NCBI Official Synonym Symbols
GCF2; TRIP; FLAP1; GCF-2; FLAP-1; HUFI-1; FLIIAP1
  [Similar Products]
NCBI Protein Information
leucine-rich repeat flightless-interacting protein 1; GC-binding factor 2; NEDD8-conjugating enzyme; TAR RNA-interacting protein; LRR FLII-interacting protein 1
UniProt Protein Name
Leucine-rich repeat flightless-interacting protein 1
UniProt Synonym Protein Names
GC-binding factor 2; TAR RNA-interacting protein
UniProt Gene Name
LRRFIP1  [Similar Products]
UniProt Synonym Gene Names
GCF2; TRIP; LRR FLII-interacting protein 1  [Similar Products]
UniProt Entry Name
LRRF1_HUMAN
UniProt Comments for LRRFIP1
LRRFIP1: Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. Belongs to the LRRFIP family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; RNA-binding

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: cytoskeleton; cytoplasm; plasma membrane; cytosol; nucleus

Molecular Function: protein binding; protein homodimerization activity; DNA binding; double-stranded RNA binding

Biological Process: regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; positive regulation of interferon type I production; innate immune response; negative regulation of transcription, DNA-dependent
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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