View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List LXA4 elisa kit :: Rat Lipoxin A4 ELISA Kit Catalog # MBS755644 Unit / Price 48-Strip-Wells / $495 +1 FREE 8GB USB 96-Strip-Wells / $700 +1 FREE 8GB USB 5x96-Strip-Wells / $3,105 +3 FREE 8GB USB 10x96-Strip-Wells / $5,865 +7 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Lipoxin A4 (LXA4), ELISA Kit Popular Item Full Product Name Rat Lipoxin A4 ELISA Kit Product Gene Name LXA4 elisa kit[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sample Manual Insert Download Sample PDF Manual View Sample PDF Manual OMIM 136538 Species Reactivity Rat Specificity This assay has high sensitivity and excellent specificity for detection of LXA4. No significant cross-reactivity or interference between LXA4 and analogues was observed. NOTE: Limited by current skills and knowledge, it is impossible for us to complete the cross-reactivity detection between LXA4 and all the analogues, therefore, cross reaction may still exist in some cases. Samples Serum, plasma, cell culture supernatants, body fluid and tissue homogenate Assay Type Quantitative Competitive Sensitivity 0.1 ng/mL Preparation and Storage Store all reagents at 2-8 degree C. Sample Preparation We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team ISO Certification Manufactured in an ISO 13485:2016 Certified Laboratory. Product Note Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details. Other Notes Small volumes of LXA4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. Searchable Terms for LXA4 purchase MBS755644 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Lipoxin A4 (LXA4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing LXA4. The ELISA analytical biochemical technique of the MBS755644 kit is based on LXA4 antibody-LXA4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LXA4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LXA4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%). TOP Related Product Information for LXA4 elisa kit Intended Uses: This LXA4 ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Rat LXA4. This ELISA kit for research use only, not for therapeutic or test applications!Principle of the Assay: LXA4 ELISA kit applies the competitive enzyme immunoassay technique utilizing a polyclonal anti-LXA4 antibody and an LXA4-HRP conjugate. The assay sample and buffer are incubated together with LXA4-HRP conjugate in pre-coated plate for one hour. After the incubation period, the wells are decanted and washed five times. The wells are then incubated with a substrate for HRP enzyme. The product of the enzyme-substrate reaction forms a blue colored complex. Finally, a stop solution is added to stop the reaction, which will then turn the solution yellow. The intensity of color is measured spectrophotometrically at 450nm in a microplate reader. The intensity of the color is inversely proportional to the LXA4 concentration since LXA4 from samples and LXA4-HRP conjugate compete for the anti-LXA4 antibody binding site. Since the number of sites is limited, as more sites are occupied by LXA4 from the sample, fewer sites are left to bind LXA4-HRP conjugate. A standard curve is plotted relating the intensity of the color (O.D.) to the concentration of standards. The LXA4 concentration in each sample is interpolated from this standard curve. Typical Testing Data/Standard Curve (for reference only) of LXA4 elisa kit TOP Sample Manual Insert of MBS755644. NCBI/Uniprot data below describe general gene information for LXA4. It may not necessarily be applicable to this product. NCBI GI # 1916076 NCBI GeneID 2358 NCBI Accession # AAB51133.1 [Other Products] UniProt Secondary Accession # A8K3E2[Other Products] UniProt Related Accession # P25090; AAB23104[Other Products] Molecular Weight 38,964 Da TOP NCBI Official Full Name lipoxin A4 receptor NCBI Official Synonym Full Names formyl peptide receptor 2 NCBI Official Symbol FPR2 [Similar Products] NCBI Official Synonym Symbols ALXR; HM63; FMLPX; FPR2A; FPRH1; FPRH2; FPRL1; LXA4R; FMLP-R-II [Similar Products] NCBI Protein Information N-formyl peptide receptor 2; RFP; FMLP-R-I; LXA4 receptor; FMLP-related receptor I; formyl peptide receptor-like 1; lipoxin A4 receptor (formyl peptide receptor related) UniProt Protein Name N-formyl peptide receptor 2 UniProt Synonym Protein Names FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP UniProt Gene Name FPR2 [Similar Products] UniProt Synonym Gene Names FPRH1; FPRL1; LXA4R; FMLP-R-I; LXA4 receptor [Similar Products] UniProt Entry Name FPR2_HUMAN TOP TOP UniProt Comments for LXA4 FPR2: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor, GPCRChromosomal Location of Human Ortholog: 19q13.3-q13.4Cellular Component: integral to membrane; plasma membraneMolecular Function: G-protein coupled receptor activity; N-formyl peptide receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; inflammatory response; cell adhesion; chemotaxis; cell motility Research Articles on LXA4 1. We also found that human mast cells expressed the N-formyl-peptide receptor 1 (FPRL1) receptor and FPRL1-specific inhibitor affected pleurocidin-mediated activation of mast cell. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with LXA4 elisa kit Reference Product PubMed Publications FPR1 elisa kit >67 publications with LXA4 and FPR1 ANXA1 elisa kit >22 publications with LXA4 and ANXA1 CXCR2 elisa kit >5 publications with LXA4 and CXCR2 CXCR1 elisa kit >4 publications with LXA4 and CXCR1 PLAUR elisa kit >3 publications with LXA4 and PLAUR CCR1 elisa kit >2 publications with LXA4 and CCR1 APP elisa kit >2 publications with LXA4 and APP Pathways associated with LXA4 elisa kit Products by Pathway Pathway Diagram Class A/1 (Rhodopsin-like Receptors) Pathway antibodies Class A/1 (Rhodopsin-like Receptors) Pathway Diagram Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway antibodies Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway Diagram G Alpha (i) Signalling Events Pathway antibodies G Alpha (i) Signalling Events Pathway Diagram G Alpha (q) Signalling Events Pathway antibodies G Alpha (q) Signalling Events Pathway Diagram GPCR Downstream Signaling Pathway antibodies GPCR Downstream Signaling Pathway Diagram GPCR Ligand Binding Pathway antibodies GPCR Ligand Binding Pathway Diagram GPCRs, Class A Rhodopsin-like Pathway antibodies GPCRs, Class A Rhodopsin-like Pathway Diagram Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram Neuroactive Ligand-receptor Interaction Pathway antibodies Neuroactive Ligand-receptor Interaction Pathway Diagram Neuroactive Ligand-receptor Interaction Pathway antibodies Neuroactive Ligand-receptor Interaction Pathway Diagram Diseases associated with LXA4 elisa kit Disease Name Pubmed Publications Inflammation Antibodies >176 publications with LXA4 and Inflammation Necrosis Antibodies >29 publications with LXA4 and Necrosis Lung Diseases Antibodies >23 publications with LXA4 and Lung Diseases Vascular Diseases Antibodies >17 publications with LXA4 and Vascular Diseases Autoimmune Diseases Antibodies >15 publications with LXA4 and Autoimmune Diseases Respiratory Hypersensitivity Antibodies >8 publications with LXA4 and Respiratory Hypersensitivity Fibrosis Antibodies >8 publications with LXA4 and Fibrosis Lung Injury Antibodies >8 publications with LXA4 and Lung Injury Respiratory Tract Infections Antibodies >6 publications with LXA4 and Respiratory Tract Infections Carcinoma Antibodies >5 publications with LXA4 and Carcinoma Organs/Tissues associated with LXA4 elisa kit Organ/Tissue Name Pubmed Publications Blood Antibodies >189 publications with LXA4 and Blood Lung Antibodies >45 publications with LXA4 and Lung Kidney Antibodies >13 publications with LXA4 and Kidney Bone Marrow Antibodies >11 publications with LXA4 and Bone Marrow Spleen Antibodies >8 publications with LXA4 and Spleen Connective Tissue Antibodies >6 publications with LXA4 and Connective Tissue Heart Antibodies >5 publications with LXA4 and Heart Placenta Antibodies >3 publications with LXA4 and Placenta Testis Antibodies >1 publications with LXA4 and Testis TOP © 2006-24 MyBioSource.com. 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