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LYZ protein :: Lysozyme Protein

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Catalog # MBS173158
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LYZ protein
Product Name

Lysozyme (LYZ), Protein

Popular Item
Full Product Name

Lysozyme, Human Neutrophils

Product Synonym Names
Lysozyme, Human Neutrophils - >=95% (SDS-PAGE)
Product Gene Name
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Purity/Purification
>= 95% (SDS-PAGE)
Form/Format
Liquid
Appearance: Clear, colorless solution
Source
Human Neutrophils
EC Number
3.2.1.17
Recertification
1 year
Protein
1.0 - 3.0 mg protein/mL (A280 E=2.5)
CAS Number
900-63-2
Preparation and Storage
At -20 degree C
Other Notes
Small volumes of LYZ protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
LYZ protein
Custom preparations, technical support, bulk quantities and aliquoting available.

Human Lysozyme is an enzyme commonly referred to as the "body's own antibiotic" since it kills bacteria. Human Lysozyme is a an enzyme that destroys bacterial cell walls by hydrolyzing the polysaccharide component of the cell wall. Human Lysozyme is abundantly present in a number of secretions, such as tears. Human Lysozyme is present in cytoplasmic granules of the polymorphonuclear neutrophils (PMN) and released through the mucosal secretions (such as tears and saliva).

Clinical significance: Human Lysozyme levels in the blood are often increased in sarcoidosis.

Lysozyme protects against bacterial infection by breaking down the carbohydrates in bacterial cell walls, killing them. Hence, lysozyme is part of the innate immune response. In saliva it protects the oral cavity from pathogens. In times of increased inflammation, such as during inflammation of the salivary glands or after a tonsillectomy, there is an increase in lysozyme. This protein also works in synergy with the bactericidal properties of lactoferrin, another common protein found in mucosal secretions.

Lysozyme also has fungicidal properties, protecting mucosal areas from invasion by pathogenic yeast or fungi. Lysozyme has been shown to inhibit viral replication and infection such HIV. Lysozyme also interacts with and increases the function of histatin, a protein shown to be bactericidal and fungicidal.
NCBI/Uniprot data below describe general gene information for LYZ. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
~14,700
NCBI Official Full Name
lysozyme
NCBI Official Symbol
NCBI Official Synonym Symbols
BmLys
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NCBI Protein Information
lysozyme; 1,4-beta-N-acetylmuramidase
UniProt Protein Name
Lysozyme
UniProt Synonym Protein Names
1,4-beta-N-acetylmuramidase
Protein Family
UniProt Entry Name
LYS_BOMMO
UniProt Comments for LYZ
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Active against E.coli and M.luteus.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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