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M recombinant protein :: Matrix protein 1 (M) Recombinant Protein

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Catalog # MBS1256969
Unit / Price
  0.01 mg (E-Coli)  /  $235 +1 FREE 8GB USB
  0.05 mg (E-Coli)  /  $320 +1 FREE 8GB USB
  0.1 mg (E-Coli)  /  $535 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $795 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $855 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,005 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,065 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,125 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,205 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,245 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,450 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,725 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,895 +2 FREE 8GB USB
  1 mg (Yeast)  /  $1,900 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,030 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,940 +3 FREE 8GB USB
SDS-PAGE
Product Name

Matrix protein 1 (M), Recombinant Protein

Popular Item
Full Product Name

Recombinant Influenza A virus Matrix protein 1 (M)

Product Synonym Names
Matrix protein 1; M1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-252. Full Length
Sequence
MSLLTEVETY VLSIVPSGPL KAEIAQRLED VFAGKNTDLE ALMEWLKTRP ILSPLTKGIL GFVFTLTVPS ERGLQRRRFV QNALNGNGDP NNMDRAVKLY RKLKREITFH GAKEIALSYS AGALASCMGL IYNRMGAVTT EVAFGLVCAT CEQIADSQHR SHRQMVTTTN PLIRHENRMV LASTTAKAME QMAGSSEQAA EAMEVASQAR QMVQAMRAIG THPSSSAGLK NDLLENLQAY QKRMGVQMQR FK
3D Structure
ModBase 3D Structure for A4GCL0
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Influenza A virus (strain A/USA:Iowa/1943 H1N1)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of M recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
M recombinant protein
Plays critical roles in virus replication, from virus entry and uncoating to assembly and budding of the virus particle. M1 binding to ribonucleocapsids (RNPs) in nucleus seems to inhibit viral transcription. Interaction of viral NEP with M1-RNP is thought to promote nuclear export of the complex, which is targeted to the virion assembly site at the apical plasma membrane in polarized epithelial cells. Interactions with NA and HA may bring M1, a non-raft-associated protein, into lipid rafts. Forms a continuous shell on the inner side of the lipid bilayer in virion, where it binds the RNP. During virus entry into cell, the M2 ion channel acidifies the internal virion core, inducing M1 dissociation from the RNP. M1-free RNPs are transported to the nucleus, where viral transcription and replication can take place
Determines the virion's shape: spherical or filamentous. Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology. Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms

M recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for M. It may not necessarily be applicable to this product.
NCBI GI #
NCBI Accession #
UniProt Primary Accession #
Molecular Weight
11,178 Da[Similar Products]
NCBI Official Full Name
Matrix protein 1
UniProt Protein Name
Matrix protein 1
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
M1_I43A0
UniProt Comments for M
Plays critical roles in virus replication, from virus entry and uncoating to assembly and budding of the virus particle. M1 binding to ribonucleocapsids (RNPs) in nucleus seems to inhibit viral transcription. Interaction of viral NEP with M1-RNP is thought to promote nuclear export of the complex, which is targeted to the virion assembly site at the apical plasma membrane in polarized epithelial cells. Interactions with NA and HA may bring M1, a non-raft-associated protein, into lipid rafts. Forms a continuous shell on the inner side of the lipid bilayer in virion, where it binds the RNP. During virus entry into cell, the M2 ion channel acidifies the internal virion core, inducing M1 dissociation from the RNP. M1-free RNPs are transported to the nucleus, where viral transcription and replication can take place ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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