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M2 recombinant protein :: Matrix protein 2 (M) Recombinant Protein

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Catalog # MBS1039980
Unit / Price
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  0.5 mg (E-Coli)  /  $815 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $815 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,040 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,040 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,100 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,100 +1 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $1,560 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,560 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,595 +1 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,180 +2 FREE 8GB USB
M2 recombinant protein
Product Name

Matrix protein 2 (M) (M2), Recombinant Protein

Full Product Name

Recombinant Influenza A virus Matrix protein 2 (M), partial

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
44-97. Partial, provide the Intravirion domain
Sequence
DRLFFKCIYR RFKYGLKGGP STEGVPKSMR EEYRKEQQSA VDADDGHFVS IELE
3D Structure
ModBase 3D Structure for P06821
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of M2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for M2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
27,893 Da[Similar Products]
NCBI Official Full Name
matrix protein 2
NCBI Official Symbol
NCBI Protein Information
M2
UniProt Protein Name
Matrix protein 2
UniProt Synonym Protein Names
Proton channel protein M2
Protein Family
UniProt Gene Name
UniProt Comments for M2
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome triggers M2 ion channel activity. The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur. Also plays a role in viral proteins secretory pathway. Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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