BC109187
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
13,016 Da
NCBI Official Full Name
Homo sapiens melanoma antigen family A, 5, mRNA
NCBI Official Synonym Full Names
MAGE family member A5
NCBI Protein Information
melanoma-associated antigen 5
UniProt Protein Name
Melanoma-associated antigen 5
UniProt Synonym Protein Names
Cancer/testis antigen 1.5; CT1.5; MAGE-5 antigen
UniProt Synonym Gene Names
UniProt Entry Name
MAGA5_HUMAN
NCBI Summary for MAGEA5
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This MAGEA gene encodes a protein that is C-terminally truncated compared to other family members, and this gene can be alternatively interpreted to be a pseudogene. The protein is represented in this Gene record in accordance with the assumed protein-coding status defined in the literature. Read-through transcription exists between this gene and the upstream melanoma antigen family A, 10 (MAGEA10) gene. [provided by RefSeq, Oct 2011]
UniProt Comments for MAGEA5
MAGE-A5: Not known, though may play a role tumor transformation or progression. In vitro promotes cell viability in melanoma cell lines.
Protein type: Cancer Testis Antigen (CTA)
Chromosomal Location of Human Ortholog: Xq28
Research Articles on MAGEA5
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
|