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MAOB western blot control :: Monoamine Oxidase B (MAOB) Western Blot Control

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Catalog # MBS343092
Unit / Price
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  0.01 mg  /  $220 +1 FREE 8GB USB
MAOB western blot control
Product Name

Monoamine Oxidase B (MAOB), Western Blot Control

Full Product Name

Monoamine Oxidase B (MAOB) (Western Blot Control)

Product Synonym Names
Amine oxidase [flavin-containing] B, Monoamine oxidase type B, MAOB, Mao Platelet, MAO Brain; MAOB (Western Blot Control)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
309860
3D Structure
ModBase 3D Structure for P27338
Purity/Purification
>= 95% (SDS PAGE)
Form/Format
Liquid
Buffer
Buffered 50% glycerol
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of MAOB western blot control vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
MAOB western blot control
Monoamine oxidase B (MAO-B) is a flavin-containing mitochondrial enzyme, which catalyzes the oxidative deamination of biogenic and xenobiotic monoamines. It regulates the metabolic degradation of catecholamines and serotonin in neural and other target tissues. MAO-B is found platelets and in dopamine-secreting neurons in the brain. Increased levels of MAO B that have been identified in brain of Alzheimer's patients. Monoamine oxidases (MAO B and MAO A) are well-known targets for antidepressant drugs and for drugs used to treat neurological disorders and aging diseases, such as Parkinson's and Alzheimer's disease. Recombinant MAO-B comprises a 488 amino acid fragment (2-489) corresponding to the cytoplasmic domain fragment of the mature MAO-B protein and is expressed in E Coli with an amino-terminal hexahistidine tag. This product is not intended for therapeutic use.
NCBI/Uniprot data below describe general gene information for MAOB. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
46,539 Da
NCBI Official Full Name
monoamine oxidase B, partial
NCBI Official Synonym Full Names
monoamine oxidase B
NCBI Official Symbol
NCBI Protein Information
amine oxidase [flavin-containing] B
UniProt Protein Name
Amine oxidase [flavin-containing] B
UniProt Synonym Protein Names
Monoamine oxidase type B; MAO-B
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
MAO-B  [Similar Products]
UniProt Entry Name
AOFB_HUMAN
NCBI Summary for MAOB
The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq, Jul 2008]
UniProt Comments for MAOB
MAOB: Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. Belongs to the flavin monoamine oxidase family.

Protein type: Amino Acid Metabolism - tryptophan; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - histidine; Xenobiotic Metabolism - drug metabolism - cytochrome P450; EC 1.4.3.4; Oxidoreductase; Membrane protein, integral; Amino Acid Metabolism - phenylalanine; Mitochondrial; Amino Acid Metabolism - arginine and proline; Amino Acid Metabolism - glycine, serine and threonine

Chromosomal Location of Human Ortholog: Xp11.23

Cellular Component: mitochondrial envelope; mitochondrial outer membrane; mitochondrion

Molecular Function: amine oxidase activity; electron carrier activity

Biological Process: dopamine catabolic process; substantia nigra development
Product References and Citations for MAOB western blot control
Binda, C. et al., Neurology 2006 67: S5-S7. Li, M. et al., Protei Expr Purif. 2002 24 (1): 152-62.

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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