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MAS1 cdna clone

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Catalog # MBS1267205
Unit / Price
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
MAS1 cdna clone
Product Name

MAS1, cDNA Clone

Popular Item
Full Product Name

MAS1 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggatgggt caaacgtgac atcatttgtt gttgaggaac ccacgaacat ctcaactggc aggaacgcct cagtcgggaa tgcacatcgg caaatcccca tcgtgcactg ggtcattatg agcatctccc cagtggggtt tgttgagaat gggattctcc tctggttcct gtgcttccgg atgagaagaa atcccttcac tgtctacatc acccacctgt ctatcgcaga catctcactg ctcttctgta ttttcatctt gtctatcgac tatgctttag attatgagct ttcttctggc cattactaca caattgtcac attatcagtg acttttctgt ttggctacaa cacgggcctc tatctgctga cggccattag tgtggagagg tgcctgtcag tcctttaccc catctggtac cgatgccatc gccccaagta ccagtcggca ttggtctgtg cccttctgtg ggctctttct tgcttggtga ccaccatgga gtatgtcatg tgcatcgaca gagaagaaga gagtcactct cggaatgact gccgagcagt catcatcttt atagccatcc tgagcttcct ggtcttcacg cccctcatgc tggtgtccag caccatcttg gtcgtgaaga tccggaagaa cacgtgggct tcccattcct ccaagcttta catagtcatc atggtcacca tcattatatt cctcatcttc gctatgccca tgagactcct ttacctgctg tactatgagt attggtcgac ctttgggaac ctacaccaca tttccctgct cttctccaca atcaacagta gcgccaaccc tttcatttac ttctttgtgg gaagcagtaa gaagaagaga ttcaaggagt ccttaaaagt tgttctgacc agggctttca aagatgaaat gcaacctcgg cgccagaaag acaattgtaa tacggtcaca gttgagactg tcgtctaa
Chromosome Location
Chromosome: 6; NC_000006.11 (160327974..160329108). Location: 6q25.3-q26
OMIM
165180
3D Structure
ModBase 3D Structure for P04201
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of MAS1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for MAS1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
37,465 Da
NCBI Official Full Name
Homo sapiens MAS1 oncogene, mRNA
NCBI Official Synonym Full Names
MAS1 oncogene
NCBI Official Symbol
NCBI Official Synonym Symbols
NCBI Protein Information
proto-oncogene Mas
UniProt Protein Name
Proto-oncogene Mas
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
MAS_HUMAN
NCBI Summary for MAS1
This gene encodes a class I seven-transmembrane G-protein-coupled receptor. The encoded protein is a receptor for angiotensin-(1-7) and preferentially couples to the Gq protein, activating the phospholipase C signaling pathway. The encoded protein may play a role in multiple processes including hypotension, smooth muscle relaxation and cardioprotection by mediating the effects of angiotensin-(1-7). [provided by RefSeq, May 2012]
UniProt Comments for MAS1
MAS1: Receptor for angiotensin 1-7. Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1. The MAS oncogene has a weak focus-inducing activity in transfected NIH 3T3 cells. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Oncoprotein

Chromosomal Location of Human Ortholog: 6q25.3-q26

Cellular Component: cell surface; integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; angiotensin type II receptor activity; peptide hormone binding; peptide binding; angiotensin receptor activity

Biological Process: response to drug; anatomical structure morphogenesis; hippocampus development; male gonad development; activation of NF-kappaB-inducing kinase; cell proliferation; G-protein coupled receptor protein signaling pathway; negative regulation of protein amino acid phosphorylation; positive regulation of cell proliferation; regulation of inflammatory response; spermatogenesis; response to activity; positive regulation of DNA replication
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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