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MGST1 blocking peptide

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Catalog # MBS9224793
Unit / Price
  0.1 mg  /  $155 +1 FREE 8GB USB
MGST1 blocking peptide
Product Name

MGST1, Blocking Peptide

Full Product Name

MGST1 Antibody (Center) Blocking Peptide

Product Synonym Names
Microsomal glutathione S-transferase 1; Microsomal GST-1; Microsomal GST-I; MGST1; GST12; MGST
Product Synonym Gene Name
GST12; MGST[Similar Products]
Antibody/Peptide Pairs
MGST1 peptide (MBS9224793) is used for blocking the activity of MGST1 antibody (MBS9206548)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
138330
3D Structure
ModBase 3D Structure for P10620
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the Center region of human MGST1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Microsome. Mitochondrion outer membrane; Peripheral membrane protein Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location
Highly expressed in liver.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of MGST1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
MGST1 blocking peptide
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a wide substrate specificity.
NCBI/Uniprot data below describe general gene information for MGST1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
9,984 Da
NCBI Official Full Name
Microsomal glutathione S-transferase 1
NCBI Official Synonym Full Names
microsomal glutathione S-transferase 1
NCBI Official Symbol
MGST1  [Similar Products]
NCBI Official Synonym Symbols
MGST; GST12; MGST-I
  [Similar Products]
NCBI Protein Information
microsomal glutathione S-transferase 1
UniProt Protein Name
Microsomal glutathione S-transferase 1
UniProt Synonym Protein Names
Microsomal GST-I
UniProt Gene Name
MGST1  [Similar Products]
UniProt Synonym Gene Names
GST12; MGST; Microsomal GST-1  [Similar Products]
UniProt Entry Name
MGST1_HUMAN
NCBI Summary for MGST1
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Several transcript variants, some non-protein coding and some protein coding, have been found for this gene. [provided by RefSeq, May 2012]
UniProt Comments for MGST1
MGST1: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a wide substrate specificity. Belongs to the MAPEG family.

Protein type: Xenobiotic Metabolism - metabolism by cytochrome P450; Mitochondrial; EC 2.5.1.18; Transferase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Membrane protein, multi-pass; Membrane protein, integral; Other Amino Acids Metabolism - glutathione

Chromosomal Location of Human Ortholog: 12p12.3-p12.1

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; mitochondrion; peroxisomal membrane

Molecular Function: glutathione peroxidase activity; glutathione transferase activity; protein binding

Biological Process: xenobiotic metabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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