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MLC1 elisa kit :: Human megalencephalic leukoencephalopathy with subcortical cysts 1 ELISA Kit

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Catalog # MBS9337225
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MLC1 elisa kit
Product Name

megalencephalic leukoencephalopathy with subcortical cysts 1 (MLC1), ELISA Kit

Popular Item
Full Product Name

Human Membrane protein MLC1, MLC1 ELISA Kit

Product Synonym Names
Human Membrane protein MLC1 (MLC1) ELISA kit; RP3-355C18.4; KIAA0027; LVM; MLC; VL; megalencephalic leukoencephalopathy with subcortical cysts 1 gene product; megalencephalic leukoencephalopathy with subcortical cysts 1
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
3D Structure
ModBase 3D Structure for Q15049
Species Reactivity
No significant cross-reactivity or interference between this analyte and analogues is observed.
Assay Type
Detection Range
31.2 ng/ml - 1000 ng/ml.
The sensitivity of this kit is 5.0 ng/ml.
Intra-assay Precision
Intra-assay CV (%) is less than 15%.
Inter-assay Precision
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of MLC1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for MLC1purchase
MBS9337225 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the megalencephalic leukoencephalopathy with subcortical cysts 1 (MLC1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MLC1. The ELISA analytical biochemical technique of the MBS9337225 kit is based on MLC1 antibody-MLC1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MLC1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MLC1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Related Product Information for
MLC1 elisa kit
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MLC1 (hereafter termed this analyte) in undiluted original Human body fluids, tissue homogenates, secretions and feces samples.
Sample Manual Insert of MBS9337225. Click to request current manual
NCBI/Uniprot data below describe general gene information for MLC1. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
41,141 Da
NCBI Official Full Name
membrane protein MLC1
NCBI Official Synonym Full Names
megalencephalic leukoencephalopathy with subcortical cysts 1
NCBI Official Symbol
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
membrane protein MLC1
UniProt Protein Name
Membrane protein MLC1
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
KIAA0027; WKL1  [Similar Products]
UniProt Entry Name
NCBI Summary for MLC1
The function of this gene product is unknown; however, homology to other proteins suggests that it may be an integral membrane transporter. Mutations in this gene have been associated with megalencephalic leukoencephalopathy with subcortical cysts, an autosomal recessive neurological disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
UniProt Comments for MLC1
MLC1: Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx. Defects in MLC1 are a cause of leukoencephalopathy megalencephalic with subcortical cysts type 1 (MLC1). MLC1 is a syndrome of cerebral leukoencephalopathy and megalencephaly characterized by ataxia, spasticity, seizures, delay in motor development and mild mental retardation. The brain appears swollen on magnetic resonance imaging, with diffuse white- matter abnormalities and the invariable presence of subcortical cysts in frontal and temporal lobes.

Protein type: Transporter; Membrane protein, multi-pass; Cell surface; Membrane protein, integral

Chromosomal Location of Human Ortholog: 22q13.33

Cellular Component: clathrin-coated vesicle; endoplasmic reticulum; lysosome; basolateral plasma membrane; early endosome; integral to membrane; caveola; intercellular junction; lipid raft; recycling endosome; perinuclear region of cytoplasm; cytoplasm; apical plasma membrane; plasma membrane; cytoplasmic vesicle; endosome

Molecular Function: protein binding; transporter activity; protein complex binding; protein transporter activity

Biological Process: vesicle-mediated transport; protein transport; transport; positive regulation of intracellular transport; ion transport; protein oligomerization; regulation of response to osmotic stress

Disease: Megalencephalic Leukoencephalopathy With Subcortical Cysts 1
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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