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MLLT10 cdna clone

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Catalog # MBS1268511
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
MLLT10 cdna clone
Product Name

MLLT10, cDNA Clone

Also Known As

MLLT10 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
381
Sequence
atggtctcta gcgaccggcc cgtgtcactg gaggacgagg tctcccatag tatgaaggag atgattggag gctgttgcgt ttgctcagac gagagaggct gggccgagaa cccgctggtt tattgcgacg ggcacggctg cagcgtcgcg gtgcatcaag cttgctatgg cattgttcaa gtacccactg gaccgtggtt ttgcaggaaa tgtgaatctc aggagagagc agccagagtg gcagagtctc gctctgttgc ccaggctaaa gtgcagtggt gtgatctcag cccactgcaa cctctgctcc ccgggttcaa gcgattctcc tgcctcagcc tcccaaatgg tatgcaattc ctgttggtta gcctcatctg a
OMIM
602409
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of MLLT10 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for MLLT10. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
20,047 Da
NCBI Official Full Name
Homo sapiens myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10, mRNA
NCBI Official Synonym Full Names
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10
NCBI Official Symbol
MLLT10  [Similar Products]
NCBI Official Synonym Symbols
NCBI Protein Information
protein AF-10
UniProt Protein Name
Protein AF-10
UniProt Synonym Protein Names
ALL1-fused gene from chromosome 10 protein
Protein Family
UniProt Gene Name
MLLT10  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
AF10_HUMAN
NCBI Summary for MLLT10
This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]
UniProt Comments for MLLT10
MLLT10: Probably involved in transcriptional regulation. In vitro or as fusion protein with MLL has transactivation activity. Binds to cruciform DNA. A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t(10;11)(p12;q23) with MLL/HRX. The result is a rogue activator protein. A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t(10;11)(p13;q14) with PICALM. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; Oncoprotein

Chromosomal Location of Human Ortholog: 10p12

Cellular Component: cytoplasm; nucleoplasm; nucleus; protein complex

Molecular Function: protein binding

Biological Process: positive regulation of transcription from RNA polymerase II promoter

Disease: Leukemia, Acute Myeloid
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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