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MMAA elisa kit :: Human methylmalonic aciduria (cobalamin deficiency) cblA type ELISA Kit

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Catalog # MBS9323020
Unit / Price
  48-Strip-Wells  /  $470 +1 FREE 8GB USB
  96-Strip-Wells  /  $680 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
MMAA elisa kit
Product Name

methylmalonic aciduria (cobalamin deficiency) cblA type (MMAA), ELISA Kit

Also Known As

Human Methylmalonic aciduria type A protein, mitochondrial, MMAA ELISA Kit

Product Synonym Names
Human Methylmalonic aciduria type A protein; mitochondrial (MMAA) ELISA kit; MGC120010; MGC120011; MGC120012; MGC120013; cblA; methylmalonic aciduria type A; methylmalonic aciduria (cobalamin deficiency) cblA type
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
607481
3D Structure
ModBase 3D Structure for Q8IVH4
Species Reactivity
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of MMAA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forMMAApurchase
MBS9323020 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the methylmalonic aciduria (cobalamin deficiency) cblA type (MMAA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MMAA. The ELISA analytical biochemical technique of the MBS9323020 kit is based on MMAA antibody-MMAA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MMAA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MMAA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Sample Manual Insert of MBS9323020. Click to request current manual
NCBI/Uniprot data below describe general gene information for MMAA. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
46,538 Da
NCBI Official Full Name
methylmalonic aciduria type A protein, mitochondrial
NCBI Official Synonym Full Names
methylmalonic aciduria (cobalamin deficiency) cblA type
NCBI Official Symbol
NCBI Official Synonym Symbols
NCBI Protein Information
methylmalonic aciduria type A protein, mitochondrial
UniProt Protein Name
Methylmalonic aciduria type A protein, mitochondrial
Protein Family
UniProt Gene Name
UniProt Entry Name
MMAA_HUMAN
NCBI Summary for MMAA
The protein encoded by this gene is involved in the translocation of cobalamin into the mitochondrion, where it is used in the final steps of adenosylcobalamin synthesis. Adenosylcobalamin is a coenzyme required for the activity of methylmalonyl-CoA mutase. Defects in this gene are a cause of methylmalonic aciduria. [provided by RefSeq, Jul 2008]
UniProt Comments for MMAA
MMAA: Probable GTPase. May function as chaperone. May be involved in the transport of cobalamin (Cbl) into mitochondria for the final steps of adenosylcobalamin (AdoCbl) synthesis. Defects in MMAA are the cause of methylmalonic aciduria type cblA (MMAA); also known as methylmalonic aciduria type A or vitamin B12-responsive methylmalonicaciduria of cblA complementation type. MMAA is a disorder of methylmalonate and cobalamin metabolism due to defective synthesis of adenosylcobalamin. Inheritance is autosomal recessive. Belongs to the ArgK family.

Protein type: Chaperone; EC 3.6.-.-

Chromosomal Location of Human Ortholog: 4q31.21

Cellular Component: mitochondrial matrix

Molecular Function: GTP binding; hydrolase activity

Biological Process: vitamin metabolic process; fatty acid beta-oxidation; short-chain fatty acid catabolic process; cobalamin metabolic process; cobalamin biosynthetic process; cellular lipid metabolic process; water-soluble vitamin metabolic process

Disease: Methylmalonic Aciduria, Cbla Type
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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