NP_079032.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
104,409 Da
NCBI Official Full Name
multimerin-2
NCBI Official Synonym Full Names
multimerin 2
NCBI Protein Information
multimerin-2; endoGlyx-1 p125/p140 subunit; EMILIN-like protein EndoGlyx-1; elastin microfibril interfacer 3; elastin microfibril interface located protein 3
UniProt Protein Name
Multimerin-2
UniProt Synonym Protein Names
EMILIN-3; Elastin microfibril interface located protein 3; Elastin microfibril interfacer 3; EndoGlyx-1 p125/p140 subunit
UniProt Synonym Gene Names
UniProt Entry Name
MMRN2_HUMAN
NCBI Summary for MMRN2
This gene encodes a protein belonging to the member of elastin microfibril interface-located (EMILIN) protein family. This family member is an extracellular matrix glycoprotein that can interfere with tumor angiogenesis and growth. It serves as a transforming growth factor beta antagonist and can interfere with the VEGF-A/VEGFR2 pathway. A related pseudogene has been identified on chromosome 6. [provided by RefSeq, Aug 2012]
UniProt Comments for MMRN2
MMRN2: Heteromer of p110, p125, p140 and p200 subunits; disulfide-linked.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 10q23.2
Cellular Component: extracellular space; basement membrane
Molecular Function: protein binding
Biological Process: negative regulation of vascular endothelial growth factor receptor signaling pathway; angiogenesis
Research Articles on MMRN2
Precautions
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Diseases associated with MMRN2 elisa kit
Organs/Tissues associated with MMRN2 elisa kit
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