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MOG cdna clone

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Catalog # MBS1274713
Unit / Price
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
MOG cdna clone
Product Name

MOG, cDNA Clone

Popular Item
Full Product Name

MOG cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggcaagct tatcgagacc ctctctgccc agctgcctct gctccttcct cctcctcctc ctcctccaag tgtcttccag ctatgcaggg cagttcagag tgataggacc aagacaccct atccgggctc tggtcgggga tgaagtggaa ttgccatgtc gcatatctcc tgggaagaac gctacaggca tggaggtggg gtggtaccgc ccccccttct ctagggtggt tcatctctac agaaatggca aggaccaaga tggagaccag gcacctgaat atcggggccg gacagagctg ctgaaagatg ctattggtga gggaaaggtg actctcagga tccggaatgt aaggttctca gatgaaggag gtttcacctg cttcttccga gatcattctt accaagagga ggcagcaatg gaattgaaag tagaagatcc tttctactgg gtgagccctg gagtgctggt tctcctcgcg gtgctgcctg tgctcctcct gcagatcact gttggcctcg tcttcctctg cctgcagtac agactgagag gaaaacttcg agcagagata gagaatctcc accggacttt tgatccccac tttctgaggg tgccctgctg gaagataacc ctgtttgtaa ttgtgccggt tcttggaccc ttggttgcct tgatcatctg ctacaactgg ctacatcgaa gactagcagg gcaattcctt gaagagctac gtaagttctc ttctctctgt tataagcaga gaataaaaag ccaggaaagg gagacagaag caacaagagg aagaggcggg ctattgaggg atcacattcc cagaggaaag gaggagctgg agagcctggg tggagggaag actcctcctg ggaggtag
OMIM
159465
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of MOG cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for MOG. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
33,528 Da
NCBI Official Full Name
Homo sapiens myelin oligodendrocyte glycoprotein, mRNA
NCBI Official Synonym Full Names
myelin oligodendrocyte glycoprotein
NCBI Official Symbol
NCBI Official Synonym Symbols
BTN6; BTNL11; MOGIG2; NRCLP7
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NCBI Protein Information
myelin-oligodendrocyte glycoprotein
UniProt Protein Name
Myelin-oligodendrocyte glycoprotein
UniProt Gene Name
UniProt Entry Name
MOG_HUMAN
NCBI Summary for MOG
The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
UniProt Comments for MOG
MOG: Mediates homophilic cell-cell adhesion. Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell- cell communication. Defects in MOG are the cause of narcolepsy type 7 (NRCLP7). Neurological disabling sleep disorder, characterized by excessive daytime sleepiness, sleep fragmentation, symptoms of abnormal rapid-eye-movement (REM) sleep, cataplexy, hypnagogic hallucinations, and sleep paralysis. Cataplexy is a sudden loss of muscle tone triggered by emotions, which is the most valuable clinical feature used to diagnose narcolepsy. Human narcolepsy is primarily a sporadically occurring disorder but familial clustering has been observed. Belongs to the immunoglobulin superfamily. BTN/MOG family. 10 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 6p22.1

Biological Process: central nervous system development

Disease: Narcolepsy 7
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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